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ZNF521 抗体 (N-Term)

The 兔 多克隆 anti-ZNF521 antibody is suitable to detect ZNF521 in samples from 人. It has been validated for WB, IF 和 EIA.
产品编号 ABIN1449926
发货至: 中国
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Quick Overview for ZNF521 抗体 (N-Term) (ABIN1449926)

抗原

See all ZNF521 抗体
ZNF521 (Zinc Finger Protein 521 (ZNF521))

适用

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宿主

  • 9

克隆类型

  • 9
多克隆

标记

  • 9
This ZNF521 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 4
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    N-Term

    交叉反应 (详细)

    Species reactivity (tested):Human.

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    18 amino acid synthetic peptide near the amino terminus of Human ZNF521

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS containing 0.02 % Sodium Azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    ZNF521 (Zinc Finger Protein 521 (ZNF521))

    别名

    ZNF521

    背景

    The zinc finger protein 521 (ZNF521) is a transcription factor containing an N-terminal transcriptional repressor motif and 30 zinc finger domains. It plays a role in both erythroid cell and osteoblast differentiation during development, inhibiting the activities of early B-cell factor 1 (EBF1) in erythroid cells and Runx2 in osteoblast precursors . ZFP521 binds to both Runx2 and histone deacetylase 3 (HDAC3), promotes their association and antagonizes Runx2 transcriptional activity in a HDAC3-dependent manner, thereby regulating osteoblast differentiation, skeletal development, and bone homeostasis .Synonyms: EHZF, Early hematopoietic zinc finger protein, LIP3, LYST-interacting protein 3, Zinc finger protein 521

    基因ID

    25925

    NCBI登录号

    NP_056276
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