AKTIP 抗体 (Middle Region)
Quick Overview for AKTIP 抗体 (Middle Region) (ABIN1449900)
抗原
See all AKTIP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- NPSVHDEARE KMLTQKKPEE QHNKSVHVAG LSWVKPGSVQ PFSKEEKTVA
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交叉反应 （详细）
- Species reactivity (expected):Mouse, Rat, Chicken, Dog, African clawed frog, ZebrafishSpecies reactivity (tested):Human
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纯化方法
- Purified using peptide immunoaffinity column
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免疫原
- Synthetic peptide directed towards the middle region of human AKTIP
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anti-AKT Interacting Protein (AKTIP) (AA 1-292) antibody
AKTIP 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-AKT Interacting Protein (AKTIP) (AA 1-292) antibodyAKTIP 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2A11 unconjugated
anti-AKT Interacting Protein (AKTIP) (AA 1-292) antibodyAKTIP 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-AKT Interacting Protein (AKTIP) (AA 201-292) antibodyAKTIP 适用: 小鼠 WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-AKT Interacting Protein (AKTIP) (AA 1-292) antibodyAKTIP 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-AKT Interacting Protein (AKTIP) (AA 1-292) antibodyAKTIP 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2B2 unconjugated
anti-AKT Interacting Protein (AKTIP) (AA 1-292) antibodyAKTIP 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-AKT Interacting Protein (AKTIP) (C-Term) antibodyAKTIP 适用: 人, 小鼠, 大鼠, 犬, 兔, 斑马鱼, Cow, 豚鼠, 马, 小鸡, Bat, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-AKT Interacting Protein (AKTIP) (AA 262-288), (C-Term) antibodyAKTIP 适用: 人 WB 宿主: 兔 Polyclonal RB38675 unconjugated
anti-AKT Interacting Protein (AKTIP) (Middle Region) antibodyAKTIP 适用: 人, 小鼠, 大鼠, 犬, 兔, 斑马鱼, Cow, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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溶解方式
- Add 50 μL of distilled water to a final concentration of 1 mg/mL.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.
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- AKTIP (AKT Interacting Protein (AKTIP))
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别名
- AKTIP / FTS
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背景
- AKTIP is the component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). AKTIP regulates apoptosis by enhancing phosphorylation and activation of AKT1. AKTIP increases release of TNFSF6 via the AKT1/GSK3B/NFATC1 signaling cascade.The mouse homolog of this gene produces fused toes and thymic hyperplasia in heterozygous mutant animals while homozygous mutants die in early development. This gene may play a role in apoptosis as these morphological abnormalities are caused by altered patterns of programmed cell death. The protein encoded by this gene is similar to the ubiquitin ligase domain of other ubiquitin-conjugating enzymes but lacks the conserved cysteine residue that enables those enzymes to conjugate ubiquitin to the target protein. This protein interacts directly with serine/threonine kinase protein kinase B (PKB)/Akt and modulates PKB activity by enhancing the phosphorylation of PKB's regulatory sites. Alternative splicing results in two transcript variants encoding the same protein.Synonyms: AKT-interacting protein, FT1, Fused toes protein homolog
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基因ID
- 64400
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NCBI登录号
- NP_001012398
抗原
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