AOC2 抗体 (Middle Region)
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Quick Overview for AOC2 抗体 (Middle Region) (ABIN1449831)
抗原
See all AOC2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- AEDIPNTVTL GNRVGFLLRP YNFFDEDPSI FSPGSVYFEK GQDAGLCSIN
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交叉反应 (详细)
- Species reactivity (expected):Mouse, Bovine, Rabbit, Dog, PigSpecies reactivity (tested):Human.
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纯化方法
- Purified using peptide immunoaffinity column
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免疫原
- Synthetic peptide directed towards the middle region of human AOC2
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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溶解方式
- Add 50 μL of distilled water to a final concentration of 1 mg/mL.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store lyophilized at 2-8 °C for one month or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.
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- AOC2 (Amine Oxidase, Copper Containing 2 (Retina-Specific) (AOC2))
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别名
- AOC2 / RAO
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背景
- Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes and ammonia in the presence of copper and quinone cofactor. The protein contains several conserved motifs including the active site of amine oxidases and the histidine residues that likely bind copper. It may be a critical modulator of signal transmission in retina, possibly by degrading the biogenic amines dopamine, histamine, and putrescine. Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes and ammonia in the presence of copper and quinone cofactor. This gene shows high sequence similarity to copper amine oxidases from various species ranging from bacteria to mammals. The protein contains several conserved motifs including the active site of amine oxidases and the histidine residues that likely bind copper. It may be a critical modulator of signal transmission in retina, possibly by degrading the biogenic amines dopamine, histamine, and putrescine. This gene may be a candidate gene for hereditary ocular diseases. Alternate splicing results in multiple transcript variants.Synonyms: Amine oxidase copper-containing, Retina-specific copper amine oxidase
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基因ID
- 314
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NCBI登录号
- NP_033720
抗原
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