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DBN1 抗体 (N-Term)

The 小鼠 单克隆 anti-DBN1 antibody is suitable to detect DBN1 in samples from 人. It has been validated for WB 和 FACS.
产品编号 ABIN1449383
发货至: 中国
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Quick Overview for DBN1 抗体 (N-Term) (ABIN1449383)

抗原

See all DBN1 抗体
DBN1 (Drebrin 1 (DBN1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This DBN1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS)

克隆位点

DBN-N-03
  • 抗原表位

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    AA 1-326, N-Term

    交叉反应 (详细)

    Species reactivity (tested):Human.

    纯化方法

    Affinity Chromatography on Protein A

    免疫原

    Bacterially expressed N-terminal fragment of recombinant human drebrin (aa 1-326)

    亚型

    IgG2b
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Tris buffered saline (TBS), pH ~8.0, 15 mM Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    DBN1 (Drebrin 1 (DBN1))

    别名

    Drebrin

    背景

    Drebrin is an actin-binding protein, which is expressed mainly in neurons and plays important role in their morphogenesis. The highest level of its expression is in developing brain. Both in neurons and non-neuronal cells drebrin acts as a key regulator of actin cytoskeleton remodelling, affecting especially intercellular junctions, such as dendritic spines of neurons or the immune synapses of T cells. Decrease of drebrin amount in the brain seems to be associated with Alzheimer's disease and Down syndrome, and in case of B-cell precursor acute lymphoblastic leukemia (BCP-ALL) lower drebrin expression correlates with higher risk of relapse.Synonyms: D0S117E, DBN-1, DBN1, DKFZp434D064, Developmentally-regulated brain protein, drebrin 1

    基因ID

    1627

    NCBI登录号

    NP_004386

    UniProt

    Q16643

    途径

    Maintenance of Protein Location
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