SCIMP 抗体
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- 抗原 See all SCIMP 抗体
- SCIMP (SLP Adaptor and CSK Interacting Membrane Protein (SCIMP))
- 适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This SCIMP antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF)
- 交叉反应 （详细）
- Species reactivity (tested):Human
- 纯化方法
- Protein-A affinity chromatography
- 纯度
- > 95 % pure by SDS-PAGE
- 免疫原
- Recombinant intracellular part of human SCIMP
- 克隆位点
- NVL-07
- 亚型
- IgG2a
- Top Product
- Discover our top product SCIMP Primary Antibody
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anti-SLP Adaptor and CSK Interacting Membrane Protein (SCIMP) antibody
SCIMP 适用: 人 FACS, WB, IP, ICC 宿主: 小鼠 Monoclonal NVL-07 unconjugated
anti-SLP Adaptor and CSK Interacting Membrane Protein (SCIMP) antibody (PE)SCIMP 适用: 人 FACS 宿主: 小鼠 Monoclonal NVL-07 PE
anti-SLP Adaptor and CSK Interacting Membrane Protein (SCIMP) (AA 59-145) antibodySCIMP 适用: 人 ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-SLP Adaptor and CSK Interacting Membrane Protein (SCIMP) antibodySCIMP 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), approx. pH 7.4, 15 mM sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- SCIMP (SLP Adaptor and CSK Interacting Membrane Protein (SCIMP))
- 别名
- SCIMP (SCIMP 产品)
- 别名
- C17orf87 antibody, UNQ5783 antibody, A430084P05Rik antibody, SLP adaptor and CSK interacting membrane protein antibody, SCIMP antibody, Scimp antibody
- 背景
- SCIMP (SLP adaptor and Csk interacting membrane protein), also known as Nvl, is a palmitoylated transmembrane adaptor protein expressed in professional antigen presenting cells, most prominently in the lymph nodes and spleen. It is associated with tetraspanin-enriched microdomains (together with MHC II). There is a close relationship between SCIMP and tyrosinkinase Lyn, which is constitutively bound to it by its SH3 domain. After MHC II-mediated stimulation in the immunological synapse SCIMP becomes phosphorylated at several tyrosine residues and provides docking sites for Grb2 and SLP65 or SLP76 adaptors transducing the signal downstream, as well as for the kinase Csk with modulatory roles.Synonyms: SLP adaptor and Csk interacting membrane protein
- 基因ID
- 388325
- NCBI登录号
- NP_996986
- UniProt
- Q6UWF3
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