CDCA8 抗体 (N-Term)
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Quick Overview for CDCA8 抗体 (N-Term) (ABIN1449290)
抗原
See all CDCA8 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-280, N-Term
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特异性
- This antibody reacts with Borealin (35 kDa).
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交叉反应 (详细)
- Species reactivity (tested):Human
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纯化方法
- Protein A agarose
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免疫原
- Recombinant full-length human Borealin (1-280 aa)
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亚型
- IgG2a
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 50 % glycerol, pH 7.2. No preservative is contained.
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储存液
- Without preservative
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Upon receipt, store (in aliqouts) at -20 °C.
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- CDCA8 (Cell Division Cycle Associated 8 (CDCA8))
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别名
- CDCA8 / Borealin
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背景
- Borealin is a subunit of the chromosomal passenger complex (CPC), which is necessary for chromosome segregation and cytokinesis. While CPC shows a dynamic localization pattern during mitosis, Borealin and survivin, another subunit of CPC is essential to localize CPC at centromare from prophase to anaphase. It is thought that Borealin and survivin recruit aurora B, a kinase subunit of CPC, to inner centromare to allow phosphorylating appropriate substrates.Synonyms: Cell division cycle-associated protein 8, Dasra-B, PESCRG3, Pluripotent embryonic stem cell-related gene 3 protein, hDasra-B
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基因ID
- 55143
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NCBI登录号
- NP_060571
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UniProt
- Q53HL2
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途径
- Cell Division Cycle, M Phase
抗原
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