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SIPA1 抗体

SIPA1 适用: 小鼠, Hamster WB, IP 宿主: 小鼠 Monoclonal 2-22-9 unconjugated
产品编号 ABIN1449260
发货至: 中国
  • 抗原 See all SIPA1 抗体
    SIPA1 (Signal-Induced Proliferation-Associated 1 (SIPA1))
    适用
    • 44
    • 6
    • 2
    • 1
    • 1
    小鼠, Hamster
    宿主
    • 43
    • 2
    • 1
    • 1
    小鼠
    克隆类型
    • 44
    • 3
    单克隆
    标记
    • 19
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SIPA1 antibody is un-conjugated
    应用范围
    • 27
    • 25
    • 13
    • 13
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP)
    交叉反应 (详细)
    Species reactivity (tested):Mouse (Ba/F3, NIH/3T3, WR19L, MEF), Hamster (CHO). Does not react with Human (HL-60, Jurkat, Raji) or Rat (Rat-1).
    纯化方法
    Anion exchange column chromatography
    免疫原
    Wister rat splenocyte immunized with the baculoviral expressed recombinant mouse SPA-1
    克隆位点
    2-22-9
    亚型
    IgG2a
    Top Product
    Discover our top product SIPA1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 50 % glycerol, pH 7.2. No preservative is contained.
    储存液
    Without preservative
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Upon receipt, store (in aliqouts) at -20 °C.
  • 抗原
    SIPA1 (Signal-Induced Proliferation-Associated 1 (SIPA1))
    别名
    SIPA1 / SPA1 (SIPA1 产品)
    别名
    Spa1 antibody, SPA1 antibody, signal-induced proliferation-associated 1 antibody, Signal peptidase I (leader peptidase I) antibody, signal-induced proliferation associated gene 1 antibody, SIPA1 antibody, sipA1 antibody, Sipa1 antibody
    背景
    SPA-1 , signal-induced proliferation associated gene 1, encodes a 130 kDa protein (p130 SPA-1 ) with a domain related to Rap1 GTPase activating protein (Rap1GAP) at the N-terminus and to PDZ protein interaction domain followed by a leucine zipper motif at the C-terminus. It exhibits a specific GAP activity for Ras-related regulatory proteins Rap1 and Rap2, but not for other small GTPases. p130 SPA-1 was mostly localized at both the plasma membrane and the perinuclear membranous region co-localizing with Rap1 and Rap2. Expression of SPA-1 and rap1GAP genes tended to be segregate in various tissues, lymphoid and hematopoietic tissues expressing abundant SPA-1 transcript without rap1GAP , while those such as brain, kidney and pancreas exhibiting rap1GAP mRNA with little SPA-1 .Synonyms: GTPase-activating protein Spa-1, Signal-induced proliferation-associated protein 1, Sipa-1, Spa-1, p130 SPA-1
    基因ID
    10090
    UniProt
    P46062
    途径
    Response to Water Deprivation
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