SIPA1 抗体
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北京 101111
Quick Overview for SIPA1 抗体 (ABIN1449260)
抗原
See all SIPA1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应 （详细）
- Species reactivity (tested):Mouse (Ba/F3, NIH/3T3, WR19L, MEF), Hamster (CHO). Does not react with Human (HL-60, Jurkat, Raji) or Rat (Rat-1).
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纯化方法
- Anion exchange column chromatography
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免疫原
- Wister rat splenocyte immunized with the baculoviral expressed recombinant mouse SPA-1
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亚型
- IgG2a
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anti-Signal-Induced Proliferation-Associated 1 (SIPA1) (AA 759-927) antibody
SIPA1 适用: 人 ELISA, WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Signal-Induced Proliferation-Associated 1 (SIPA1) (C-Term) antibodySIPA1 适用: 人 WB, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Signal-Induced Proliferation-Associated 1 (SIPA1) (AA 763-1042) antibodySIPA1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Signal-Induced Proliferation-Associated 1 (SIPA1) (C-Term) antibodyVerified SIPA1 适用: 人 ELISA, WB 宿主: 山羊 Polyclonal unconjugated
anti-Signal-Induced Proliferation-Associated 1 (SIPA1) (AA 933-1042) antibodySIPA1 适用: 人 ELISA 宿主: 小鼠 Monoclonal 2B4 unconjugated
anti-Signal-Induced Proliferation-Associated 1 (SIPA1) (AA 863-912) antibodySIPA1 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Signal-Induced Proliferation-Associated 1 (SIPA1) antibodySIPA1 适用: 人 WB, IP 宿主: 小鼠 Monoclonal 331-9 unconjugated
anti-Signal-Induced Proliferation-Associated 1 (SIPA1) (N-Term) antibodySIPA1 适用: 人 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 50 % glycerol, pH 7.2. No preservative is contained.
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储存液
- Without preservative
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Upon receipt, store (in aliqouts) at -20 °C.
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- SIPA1 (Signal-Induced Proliferation-Associated 1 (SIPA1))
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别名
- SIPA1 / SPA1
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背景
- SPA-1 , signal-induced proliferation associated gene 1, encodes a 130 kDa protein (p130 SPA-1 ) with a domain related to Rap1 GTPase activating protein (Rap1GAP) at the N-terminus and to PDZ protein interaction domain followed by a leucine zipper motif at the C-terminus. It exhibits a specific GAP activity for Ras-related regulatory proteins Rap1 and Rap2, but not for other small GTPases. p130 SPA-1 was mostly localized at both the plasma membrane and the perinuclear membranous region co-localizing with Rap1 and Rap2. Expression of SPA-1 and rap1GAP genes tended to be segregate in various tissues, lymphoid and hematopoietic tissues expressing abundant SPA-1 transcript without rap1GAP , while those such as brain, kidney and pancreas exhibiting rap1GAP mRNA with little SPA-1 .Synonyms: GTPase-activating protein Spa-1, Signal-induced proliferation-associated protein 1, Sipa-1, Spa-1, p130 SPA-1
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基因ID
- 10090
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UniProt
- P46062
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途径
- Response to Water Deprivation
抗原
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