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PDCD1LG2 抗体 (Extracellular Domain)

The 大鼠 单克隆 anti-PDCD1LG2 antibody is suitable to detect PDCD1LG2 in samples from 小鼠. It has been validated for FACS.
产品编号 ABIN1449245
发货至: 中国
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Quick Overview for PDCD1LG2 抗体 (Extracellular Domain) (ABIN1449245)

抗原

See all PDCD1LG2 抗体
PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))

适用

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小鼠

宿主

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大鼠

克隆类型

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单克隆

标记

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This PDCD1LG2 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS)

克隆位点

54-1
  • 抗原表位

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    Extracellular Domain

    特异性

    This antibody reacts with mouse CD273 antigen

    纯化方法

    Protein A agarose

    免疫原

    Recombinant mouse PD-L2 extracellular domain

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS containing 50 % glycerol, pH 7.2. Contains no preservatives.

    储存液

    Without preservative

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Upon receipt, store (in aliqouts) at -20 °C.
  • 抗原

    PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))

    别名

    CD273 / PDL2

    背景

    Programmed death ligand 2 (PD-L2, also known as CD273/B7-DC), a member of B7 family was identified among a library of genes differentially expressed between DCs and activated m acrophages. PD-L2 is a ligand for programmed death 1 (PD-1) which belongs to the CD28/CTLA-4 subfamily. Engagement of PD-1 by PD-L2 dramatically inhibits T cell receptor (TCR)-mediated proliferation and cytokine production by CD4 + T cells. At low antigen concentrations, PD-L2-PD-1 interactions inhibit strong B7-CD28 signals. In contrast, at high antigen concentrations, PD-L2-PD-1 interactions reduce cytokine production but do not inhibit T cell proliferation.Synonyms: B7DC, PD-1-ligand 2, PD-L2, PDCD1 ligand 2, PDCD1L2, PDCD1LG2, Programmed cell death 1 ligand 2, Programmed death ligand 2

    基因ID

    80380

    NCBI登录号

    NP_079515

    UniProt

    Q9BQ51
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