PDCD1LG2 抗体 (Extracellular Domain)
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Quick Overview for PDCD1LG2 抗体 (Extracellular Domain) (ABIN1449245)
抗原
See all PDCD1LG2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- Extracellular Domain
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特异性
- This antibody reacts with mouse CD273 antigen
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纯化方法
- Protein A agarose
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免疫原
- Recombinant mouse PD-L2 extracellular domain
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亚型
- IgG1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 50 % glycerol, pH 7.2. Contains no preservatives.
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储存液
- Without preservative
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Upon receipt, store (in aliqouts) at -20 °C.
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- PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))
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别名
- CD273 / PDL2
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背景
- Programmed death ligand 2 (PD-L2, also known as CD273/B7-DC), a member of B7 family was identified among a library of genes differentially expressed between DCs and activated m acrophages. PD-L2 is a ligand for programmed death 1 (PD-1) which belongs to the CD28/CTLA-4 subfamily. Engagement of PD-1 by PD-L2 dramatically inhibits T cell receptor (TCR)-mediated proliferation and cytokine production by CD4 + T cells. At low antigen concentrations, PD-L2-PD-1 interactions inhibit strong B7-CD28 signals. In contrast, at high antigen concentrations, PD-L2-PD-1 interactions reduce cytokine production but do not inhibit T cell proliferation.Synonyms: B7DC, PD-1-ligand 2, PD-L2, PDCD1 ligand 2, PDCD1L2, PDCD1LG2, Programmed cell death 1 ligand 2, Programmed death ligand 2
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基因ID
- 80380
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NCBI登录号
- NP_079515
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UniProt
- Q9BQ51
抗原
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