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PSME1 抗体

PSME1 适用: 人, 小鼠, 大鼠 WB, IHC (p), IP 宿主: 小鼠 Monoclonal 1G11 unconjugated
产品编号 ABIN1449243
发货至: 中国
  • 抗原 See all PSME1 抗体
    PSME1 (Proteasome (Prosome, Macropain) Activator Subunit 1 (PA28 Alpha) (PSME1))
    适用
    • 50
    • 40
    • 37
    • 15
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 59
    • 5
    • 1
    小鼠
    克隆类型
    • 54
    • 11
    单克隆
    标记
    • 27
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
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    This PSME1 antibody is un-conjugated
    应用范围
    • 50
    • 21
    • 20
    • 14
    • 14
    • 13
    • 8
    • 6
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)
    特异性
    This antibody detects PA28α on Western blotting, Immunoprecipitation and Immunohistochemistry. Species Reactivity on Western Blot: Human: HeLa, Jurkat, Raji, HL-60, A431, U937, HEL. Mouse: L5178Y, NIH/3T3. Rat: Rat-1.Species Reactivity on Western Blot:
    交叉反应 (详细)
    Species reactivity (tested):Human, Mouse, Rat.
    免疫原
    Recombinant Mouse full length PA28alpha
    克隆位点
    1G11
    亚型
    IgG2a
    Top Product
    Discover our top product PSME1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS, pH 7.2, None, 50 % Glycerol
    储存液
    Azide free
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Upon receipt, store (in aliqouts) at -20 °C.
  • 抗原
    PSME1 (Proteasome (Prosome, Macropain) Activator Subunit 1 (PA28 Alpha) (PSME1))
    别名
    PSME1 (PSME1 产品)
    别名
    fk89d05 antibody, wu:fk89d05 antibody, IFI5111 antibody, PA28A antibody, PA28alpha antibody, REGalpha antibody, AW413925 antibody, PA28a antibody, proteasome activator subunit 1 antibody, proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) antibody, psme1 antibody, PSME1 antibody, Psme1 antibody
    背景
    PA28, also called 11S regulator, was identified as a proteasome activator that strongly increases the maximal velocity of the hydrolytic reaction and decreases the concentration of substrate required for cleavage by purified 20S proteasomes. It is known that major histocompatibility complex (MHC) class I ligands are mainly produced by the proteasome. PA28 also plays an important role in the processing of MHC class I ligands. However, isolated PA28 does not perform enzymatic activity by itself. PA28 is composed of two homologous subunits, PA28α (30 kDa) and PA28ß. These two subunits assemble into a heterohexamer (α3ß3) or a heteroheptomer (α3ß4 or mixture of α3ß4 and α4ß3). The PA28 complex is expressed constitutively in antigen presenting cells, its expression is upregulated by IFN-γIt appears to be involved in the presentation of endogenous antigen by MHC class I molecules.Synonyms: 11S regulator complex subunit alpha, Activator of multicatalytic protease subunit 1, IFI5111, IGUP I-5111, Interferon gamma up-regulated I-5111 protein, PA28a, PA28alpha, PSME-1, Proteasome activator 28 subunit alpha, Proteasome activator complex subunit 1, REG-alpha
    基因ID
    5720
    NCBI登录号
    NP_006254
    UniProt
    Q06323
    途径
    Mitotic G1-G1/S Phases, DNA Replication, Positive Regulation of Endopeptidase Activity, Synthesis of DNA
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