PSME1 抗体
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Quick Overview for PSME1 抗体 (ABIN1449243)
抗原
See all PSME1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody detects PA28α on Western blotting, Immunoprecipitation and Immunohistochemistry. Species Reactivity on Western Blot: Human: HeLa, Jurkat, Raji, HL-60, A431, U937, HEL. Mouse: L5178Y, NIH/3T3. Rat: Rat-1.Species Reactivity on Western Blot:
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交叉反应 （详细）
- Species reactivity (tested):Human, Mouse, Rat.
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免疫原
- Recombinant Mouse full length PA28alpha
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亚型
- IgG2a
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anti-Proteasome (Prosome, Macropain) Activator Subunit 1 (PA28 Alpha) (PSME1) (AA 1-249) antibody
PSME1 适用: 人 WB, ELISA, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Proteasome (Prosome, Macropain) Activator Subunit 1 (PA28 Alpha) (PSME1) (AA 72-121) antibodyPSME1 适用: 人, 小鼠, Pig, 猴, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Proteasome (Prosome, Macropain) Activator Subunit 1 (PA28 Alpha) (PSME1) (AA 1-249) antibodyPSME1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Proteasome (Prosome, Macropain) Activator Subunit 1 (PA28 Alpha) (PSME1) (AA 1-249) antibodyPSME1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Proteasome (Prosome, Macropain) Activator Subunit 1 (PA28 Alpha) (PSME1) (C-Term) antibodyPSME1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Proteasome (Prosome, Macropain) Activator Subunit 1 (PA28 Alpha) (PSME1) (AA 1-249) antibodyPSME1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Proteasome (Prosome, Macropain) Activator Subunit 1 (PA28 Alpha) (PSME1) (AA 220-249), (C-Term) antibodyPSME1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB21015 unconjugated
anti-Proteasome (Prosome, Macropain) Activator Subunit 1 (PA28 Alpha) (PSME1) antibodyPSME1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Proteasome (Prosome, Macropain) Activator Subunit 1 (PA28 Alpha) (PSME1) (AA 181-249) antibodyPSME1 适用: 小鼠, 大鼠, Cynomolgus WB, ELISA, ICC, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Proteasome (Prosome, Macropain) Activator Subunit 1 (PA28 Alpha) (PSME1) antibodyPSME1 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS, pH 7.2, None, 50 % Glycerol
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储存液
- Azide free
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Upon receipt, store (in aliqouts) at -20 °C.
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- PSME1 (Proteasome (Prosome, Macropain) Activator Subunit 1 (PA28 Alpha) (PSME1))
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别名
- PSME1
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背景
- PA28, also called 11S regulator, was identified as a proteasome activator that strongly increases the maximal velocity of the hydrolytic reaction and decreases the concentration of substrate required for cleavage by purified 20S proteasomes. It is known that major histocompatibility complex (MHC) class I ligands are mainly produced by the proteasome. PA28 also plays an important role in the processing of MHC class I ligands. However, isolated PA28 does not perform enzymatic activity by itself. PA28 is composed of two homologous subunits, PA28α (30 kDa) and PA28ß. These two subunits assemble into a heterohexamer (α3ß3) or a heteroheptomer (α3ß4 or mixture of α3ß4 and α4ß3). The PA28 complex is expressed constitutively in antigen presenting cells, its expression is upregulated by IFN-γIt appears to be involved in the presentation of endogenous antigen by MHC class I molecules.Synonyms: 11S regulator complex subunit alpha, Activator of multicatalytic protease subunit 1, IFI5111, IGUP I-5111, Interferon gamma up-regulated I-5111 protein, PA28a, PA28alpha, PSME-1, Proteasome activator 28 subunit alpha, Proteasome activator complex subunit 1, REG-alpha
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基因ID
- 5720
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NCBI登录号
- NP_006254
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UniProt
- Q06323
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途径
- Mitotic G1-G1/S Phases, DNA Replication, Positive Regulation of Endopeptidase Activity, Synthesis of DNA
抗原
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