SF3B1 抗体 (AA 98-198)
(1 reference)Quick Overview for SF3B1 抗体 (AA 98-198) (ABIN1449241)
抗原
See all SF3B1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 98-198
-
特异性
- This antibody reacts with Sap155.
-
交叉反应 （详细）
- Species reactivity (tested):Human, Mouse
-
纯化方法
- Protein A agarose
-
免疫原
- Recombinant GST-Sap155 (98 a.a.- 198 a.a.)
-
亚型
- IgG2b
-
-
anti-Splicing Factor 3b, Subunit 1, 155kDa (SF3B1) antibody
SF3B1 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Splicing Factor 3b, Subunit 1, 155kDa (SF3B1) antibodySF3B1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Monoclonal 6C7 unconjugated Recombinant Antibody
anti-Splicing Factor 3b, Subunit 1, 155kDa (SF3B1) (AA 1-144) antibodySF3B1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Splicing Factor 3b, Subunit 1, 155kDa (SF3B1) (N-Term) antibodySF3B1 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 山羊, 兔, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Splicing Factor 3b, Subunit 1, 155kDa (SF3B1) (AA 186-378) antibodySF3B1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Splicing Factor 3b, Subunit 1, 155kDa (SF3B1) (N-Term) antibodySF3B1 适用: 人, 小鼠, 大鼠, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Splicing Factor 3b, Subunit 1, 155kDa (SF3B1) (AA 374-402), (N-Term) antibodySF3B1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB33758 unconjugated
anti-Splicing Factor 3b, Subunit 1, 155kDa (SF3B1) (Middle Region) antibodySF3B1 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 山羊, 兔, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Splicing Factor 3b, Subunit 1, 155kDa (SF3B1) (Middle Region) antibodySF3B1 适用: 人, 小鼠, 大鼠, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Splicing Factor 3b, Subunit 1, 155kDa (SF3B1) (N-Term) antibodySF3B1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
浓度
- 1.0 mg/mL
-
缓冲液
- PBS containing 50 % glycerol, pH 7.2. Contains no preservatives.
-
储存液
- Without preservative
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- -20 °C
-
储存方法
- Upon receipt, store (in aliqouts) at -20 °C.
-
-
-
: "Depletion of the MFAP1/SPP381 Splicing Factor Causes R-Loop-Independent Genome Instability." in: Cell reports, Vol. 28, Issue 6, pp. 1551-1563.e7, (2020) (PubMed).
-
: "Depletion of the MFAP1/SPP381 Splicing Factor Causes R-Loop-Independent Genome Instability." in: Cell reports, Vol. 28, Issue 6, pp. 1551-1563.e7, (2020) (PubMed).
-
- SF3B1 (Splicing Factor 3b, Subunit 1, 155kDa (SF3B1))
-
别名
- SF3B1 / SAP155
-
背景
- SF3 is a U2 snRNP-associated protein complex essential for spliceosome assembly and splicing catalysis of the majo r spliceosome. SF3 contains the Spliceosome-Associated Proteins, Sap 49, 130, 145, and 155. Sap155/Sf3b1 is an essential subunit of the U2 snRNP for mRNA splicing and has also been identified in the minor (U12-dependent) sp liceosome. Sap155 interacts with the mammalian PcG (Polycomb group) proteins, Mel18 and Ring1B by the yeast two hybrid system. Sap155 contains numerous Cdk consensus phosphorylation sites in its N terminus and is phosphorylated prior to catal ytic step II of the splicing pathway. Sap155 serves as a substrate for cyclin E-cdk2 in vitro , suggesting that pre-mRNA splicing may be linked to the cell cycle machiner y in mammalian cells.Synonyms: Pre-mRNA-splicing factor SF3b 155 kDa subunit, SAP 155, SAP-155, SF3b155, Spliceosome-associated protein 155, Splicing factor 3B subunit 1
-
分子量
- 155 kDa
-
基因ID
- 23451
-
NCBI登录号
- NP_036565
-
UniProt
- O75533
-
途径
- Chromatin Binding
抗原
-
