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Histone H4 抗体

This anti-Histone H4 antibody is a 小鼠 单克隆 antibody detecting Histone H4 in WB, IF 和 IP. Suitable for 人, 小鼠, 大鼠 和 Hamster.
产品编号 ABIN1449238
发货至: 中国

Quick Overview for Histone H4 抗体 (ABIN1449238)

抗原

See all Histone H4 抗体
Histone H4

适用

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人, 小鼠, 大鼠, Hamster

宿主

  • 371
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小鼠

克隆类型

  • 342
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单克隆

标记

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This Histone H4 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)

克隆位点

C14691
  • 特异性

    This antibody reacts with Histone H4.

    交叉反应 (详细)

    Species reactivity (tested):Human, Mouse, Rat, Hamster

    纯化方法

    Protein A agarose

    免疫原

    Protein fraction extracted from the mitotic chromosome

    亚型

    IgG2b
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS containing 50 % glycerol, pH 7.2. No preservative is contained.

    储存液

    Without preservative

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Upon receipt, store (in aliqouts) at -20 °C.
  • 抗原

    Histone H4

    背景

    The nucleosome is made up of four core histone proteins (H2A, H2B, H3 and H4) and is the primary building block of chromatin. The N-terminal tail of core histones undergoes multiple different post-transcriptional modifications including acetylation, phosphorylation, ubiquitination, methylation, and ADP-ribosylation. These modifications occur in response to cell signal stimuli and have a direct effect on gene expression. Acetylation of histone H4 plays a primary role in the structural changes that mediate enhanced binding of transcription factors to their recognition sites within nucleosomes. It has been suggested that acetylated Histone H4 also is involved in heightened activation of the transcription of male X chromosomes, and that Histone H4 stimulates glucose transport activity in rat skeletal muscle.Synonyms: H4/A, H4FA, HIST1H4

    分子量

    11 kDa

    基因ID

    121504

    NCBI登录号

    NP_001029249

    UniProt

    P62805
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