CD52 抗体
Quick Overview for CD52 抗体 (ABIN1449230)
抗原
See all CD52 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody reacts with mouse CAMPATH-1/CD52.
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纯化方法
- Protein G agarose
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免疫原
- Mouse IL-2R alpha-TGM splenocyte
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亚型
- IgG2a
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anti-CD52 (CD52) antibody
CD52 适用: 人, 猕猴, Cynomolgus FACS, WB, IHC (p), ELISA, IHC (fro), CyTox, in vivo 宿主: Human Monoclonal Campath-1H unconjugated Recombinant Antibody
anti-CD52 (CD52) antibody (APC)CD52 适用: 人 FACS 宿主: 小鼠 Monoclonal HI186 APC
anti-CD52 (CD52) (AA 1-61) antibodyCD52 适用: 人 IHC, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-CD52 (CD52) (AA 20-50) antibodyCD52 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-CD52 (CD52) antibodyCD52 适用: 人, 猕猴, Cynomolgus FACS, WB, IHC (p), ELISA, IHC (fro), CyTox, in vivo 宿主: 兔 Chimeric Campath-1H unconjugated Recombinant Antibody
anti-CD52 (CD52) antibodyCD52 适用: 人 IHC (f) 宿主: 兔 Monoclonal CD52-2276R unconjugated Recombinant Antibody
anti-CD52 (CD52) antibodyCD52 适用: 人 FACS 宿主: 小鼠 Monoclonal 4C8 unconjugated
anti-CD52 (CD52) antibody (FITC)CD52 适用: 人 FACS 宿主: 小鼠 Monoclonal 4C8 FITC
anti-CD52 (CD52) antibody (PE)CD52 适用: 人 FACS 宿主: 小鼠 Monoclonal 4C8 PE
anti-CD52 (CD52) antibody (APC)CD52 适用: 人 FACS 宿主: 小鼠 Monoclonal 4C8 APC
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 50 % glycerol, pH 7.2. Contains no preservatives.
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储存液
- Without preservative
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Upon receipt, store (in aliqouts) at -20 °C.
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- CD52
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别名
- CD52 / CAMPATH-1
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背景
- CAMPATH-1, also known as CD52, is a heavily glycosylated, GPI-anchored protein expressed at high levels on almost all thymocytes, lymphocytes, monocytes, and macrophages. The function of CD52 is unknown. However, CD52 is an exceptionally good target for complement-mediated cell lysis and antibody-mediated cellular cytotoxicity. Humanized CAMPATH-1antibodies have been used therapeutically to effectively deplete lymphocytes in allogeneic bone marrow transplants, hematologic malignancies, and autoimmune diseases. Clinical trials suggest CAMPATH-1 antibodies are especially promising in the treatment of leukemia, non-Hodgkin lymphomas, and rheumatoid arthritis. The apparent size of CAMPATH-1 by SDS-PAGE is 25-29 kDa, however, the actual molecule is much smaller, ~ 8-9 kDa as confirmed by total structure analysis and mass spectrometry.Synonyms: CDw52, Cambridge pathology 1 antigen, Epididymal secretory protein E5, HE5
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基因ID
- 23833
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NCBI登录号
- NP_038734
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UniProt
- Q64389
抗原
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