This antibody reacts with CD93 antigen. mNI-11 has been reported to induce intercellular adhesion of LPS-stimulated monocyte (U937) cells as well as inducing the adhesion of these cells to an endothelial (HUVEC) cell layer and rapid spread formation in HUVECs.
Optimal working dilution should be determined by the investigator.
限制
仅限研究用
浓度
1.0 mg/mL
缓冲液
PBS containing 50 % glycerol, pH 7.2. No preservative is contained.
储存液
Without preservative
注意事项
Avoid repeated freezing and thawing.
储存条件
-20 °C
储存方法
Upon receipt, store (in aliqouts) at -20 °C.
抗原
CD93
别名
CD93 / C1QR1
背景
CD93, also known as C1qRp, is a 100-125 kDa type I membrane protein that is a receptor for the complement protein C1q. CD93 has also been shown to act as a receptor for mannose-binding lectin and surfactant protein A. CD93 is expressed on the surface of monocytes, granulocytes, and endothelial cells, and expression is increased by TNF-α or GM-CSF. CD93 is involved in ligand-mediated enhancement of phagocytosis and intercellular adhesion.Synonyms: C1q receptor, C1q/MBL/SPA receptor, CDw93, Complement component 1 q subcomponent receptor 1, Complement component C1q receptor, MBL receptor, MXRA4, Matrix-remodeling-associated protein 4, SPA receptor