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RAN 抗体

RAN 适用: 人, 小鼠, 大鼠, Hamster WB, IF, IP 宿主: 小鼠 Monoclonal ARAN1 unconjugated
产品编号 ABIN1449197
发货至: 中国
  • 抗原 See all RAN 抗体
    RAN (RAN, Member RAS Oncogene Family (RAN))
    适用
    • 87
    • 43
    • 41
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠, Hamster
    宿主
    • 81
    • 4
    • 2
    小鼠
    克隆类型
    • 82
    • 4
    单克隆
    标记
    • 42
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This RAN antibody is un-conjugated
    应用范围
    • 64
    • 34
    • 28
    • 26
    • 26
    • 17
    • 11
    • 9
    • 7
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)
    特异性
    This antibody reacts with Ran. ARAN1 inhibits the basic type NLS-dependent nuclear protein import. ARAN1 recognizes an epitope located the residues between 207 and 216 of human Ran.
    交叉反应 (详细)
    Species reactivity (tested):Human, Mouse, Rat, Hamster
    纯化方法
    Protein A agarose
    免疫原
    Recombinant human Ran
    克隆位点
    ARAN1
    亚型
    IgG2b
    Top Product
    Discover our top product RAN Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 50 % glycerol, pH 7.2. No preservative is contained.
    储存液
    Without preservative
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Upon receipt, store (in aliqouts) at -20 °C.
  • 抗原
    RAN (RAN, Member RAS Oncogene Family (RAN))
    别名
    RAN (RAN 产品)
    别名
    ARA24 antibody, Gsp1 antibody, TC4 antibody, ran antibody, ara24 antibody, gsp1 antibody, ran-1 antibody, tc4 antibody, RAN antibody, RANP1 antibody, AAF30287 antibody, CG1404 antibody, Dmel\CG1404 antibody, Ran antibody, dran antibody, l(1)G0075 antibody, ran10A antibody, fc16b04 antibody, wu:fc16b04 antibody, RAN, member RAS oncogene family antibody, RAN, member RAS oncogene family S homeolog antibody, CG1404 gene product from transcript CG1404-RC antibody, RAN antibody, Ran antibody, ran.S antibody, ran antibody
    背景
    The Ran GTPase has important roles in nucleocytoplasmic transport, cell cycle progression, nuclear organization and nuclear envelope (NE) assembly. The small GTPase Ran is essential for spindle assembly. Ran is proposed to act through its nuclear import receptors importin and/or importin to control the sequestration of proteins necessary for spindle assembly. Ran, is required for coordinating the onset of mitosis with S-phase completion in mammalian cells. Other defects in the Ran-GTPase network also result in disruption of cell-cycle processes such as DNA replication, exit from mitosis and, at least in budding yeast, accurate chromosome segregation.Synonyms: ARA24, Androgen receptor-associated protein 24, GTP-binding nuclear protein Ran, GTPase Ran, Ras-like protein TC4, Ras-related nuclear protein
    分子量
    25 kDa
    基因ID
    5901
    NCBI登录号
    NP_006316
    UniProt
    P62826
    途径
    Regulatory RNA Pathways, Intracellular Steroid Hormone Receptor Signaling Pathway, Protein targeting to Nucleus
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