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RAN 抗体

This anti-RAN antibody is a 小鼠 单克隆 antibody detecting RAN in WB, IF 和 IP. Suitable for 人, 小鼠, 大鼠 和 Hamster.
产品编号 ABIN1449197
发货至: 中国

Quick Overview for RAN 抗体 (ABIN1449197)

抗原

See all RAN 抗体
RAN (RAN, Member RAS Oncogene Family (RAN))

适用

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  • 5
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  • 2
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  • 1
  • 1
  • 1
人, 小鼠, 大鼠, Hamster

宿主

  • 80
  • 4
  • 2
小鼠

克隆类型

  • 77
  • 8
单克隆

标记

  • 46
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
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  • 2
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  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
  • 1
This RAN antibody is un-conjugated

应用范围

  • 61
  • 32
  • 26
  • 26
  • 26
  • 18
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  • 6
  • 2
  • 1
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  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)

克隆位点

ARAN1
  • 特异性

    This antibody reacts with Ran. ARAN1 inhibits the basic type NLS-dependent nuclear protein import. ARAN1 recognizes an epitope located the residues between 207 and 216 of human Ran.

    交叉反应 (详细)

    Species reactivity (tested):Human, Mouse, Rat, Hamster

    纯化方法

    Protein A agarose

    免疫原

    Recombinant human Ran

    亚型

    IgG2b
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS containing 50 % glycerol, pH 7.2. No preservative is contained.

    储存液

    Without preservative

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Upon receipt, store (in aliqouts) at -20 °C.
  • 抗原

    RAN (RAN, Member RAS Oncogene Family (RAN))

    别名

    RAN

    背景

    The Ran GTPase has important roles in nucleocytoplasmic transport, cell cycle progression, nuclear organization and nuclear envelope (NE) assembly. The small GTPase Ran is essential for spindle assembly. Ran is proposed to act through its nuclear import receptors importin and/or importin to control the sequestration of proteins necessary for spindle assembly. Ran, is required for coordinating the onset of mitosis with S-phase completion in mammalian cells. Other defects in the Ran-GTPase network also result in disruption of cell-cycle processes such as DNA replication, exit from mitosis and, at least in budding yeast, accurate chromosome segregation.Synonyms: ARA24, Androgen receptor-associated protein 24, GTP-binding nuclear protein Ran, GTPase Ran, Ras-like protein TC4, Ras-related nuclear protein

    分子量

    25 kDa

    基因ID

    5901

    NCBI登录号

    NP_006316

    UniProt

    P62826

    途径

    Regulatory RNA Pathways, Intracellular Steroid Hormone Receptor Signaling Pathway, Protein targeting to Nucleus
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