RAN 抗体
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Quick Overview for RAN 抗体 (ABIN1449197)
抗原
See all RAN 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody reacts with Ran. ARAN1 inhibits the basic type NLS-dependent nuclear protein import. ARAN1 recognizes an epitope located the residues between 207 and 216 of human Ran.
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交叉反应 (详细)
- Species reactivity (tested):Human, Mouse, Rat, Hamster
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纯化方法
- Protein A agarose
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免疫原
- Recombinant human Ran
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亚型
- IgG2b
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 50 % glycerol, pH 7.2. No preservative is contained.
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储存液
- Without preservative
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Upon receipt, store (in aliqouts) at -20 °C.
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- RAN (RAN, Member RAS Oncogene Family (RAN))
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别名
- RAN
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背景
- The Ran GTPase has important roles in nucleocytoplasmic transport, cell cycle progression, nuclear organization and nuclear envelope (NE) assembly. The small GTPase Ran is essential for spindle assembly. Ran is proposed to act through its nuclear import receptors importin and/or importin to control the sequestration of proteins necessary for spindle assembly. Ran, is required for coordinating the onset of mitosis with S-phase completion in mammalian cells. Other defects in the Ran-GTPase network also result in disruption of cell-cycle processes such as DNA replication, exit from mitosis and, at least in budding yeast, accurate chromosome segregation.Synonyms: ARA24, Androgen receptor-associated protein 24, GTP-binding nuclear protein Ran, GTPase Ran, Ras-like protein TC4, Ras-related nuclear protein
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分子量
- 25 kDa
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基因ID
- 5901
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NCBI登录号
- NP_006316
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UniProt
- P62826
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途径
- Regulatory RNA Pathways, Intracellular Steroid Hormone Receptor Signaling Pathway, Protein targeting to Nucleus
抗原
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