Optimal working dilution should be determined by the investigator.
限制
仅限研究用
浓度
1.0 mg/mL
缓冲液
PBS containing 50 % glycerol, pH 7.2. No preservative is contained.
储存液
Without preservative
注意事项
Avoid repeated freezing and thawing.
储存条件
-20 °C
储存方法
Upon receipt, store (in aliqouts) at -20 °C.
抗原
MFGE8
(Milk Fat Globule-EGF Factor 8 Protein (MFGE8))
别名
Lactadherin
背景
Apoptotic cells are rapidly removed by phagocytosis to clear the living cells and tissues of intracellular materials being released from dying cells. Phagocytes recognize apoptotic cells through milk fat globule-EGF-factor 8 (MFG-E8). MFG-E8 is a secreted glycoprotein from thioglycollate-elicited macrophages and bind to phosphatidylserine exposed on the cell surface of apoptotic cells, then bind strongly to cells expressing ανβ3 integrin via its RGD (arginine-glycine-aspartate) motif. Thus, MFG-E8 is an important protein to mediate the engulfment of apoptotic cells by activated macrophages.Synonyms: Breast epithelial antigen BA46, HMFG, MFGE8, MFGM, Milk fat globule-EGF factor 8