MARCH9 抗体 (PE-Cy5)
Quick Overview for MARCH9 抗体 (PE-Cy5) (ABIN1435559)
抗原
See all MARCH9 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human MARCH9
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亚型
- IgG
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anti-Membrane-Associated Ring Finger (C3HC4) 9 (MARCH9) (AA 240-345) antibody
MARCH9 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2B5 unconjugated
anti-Membrane-Associated Ring Finger (C3HC4) 9 (MARCH9) (N-Term) antibodyMARCH9 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Membrane-Associated Ring Finger (C3HC4) 9 (MARCH9) (C-Term) antibodyMARCH9 适用: 人, 小鼠, 大鼠, Cow, 犬, Pig, 豚鼠, 马, 兔, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Membrane-Associated Ring Finger (C3HC4) 9 (MARCH9) (AA 277-346) antibodyMARCH9 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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FCM(1:100-500)
Optimal working dilution should be determined by the investigator. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- MARCH9 (Membrane-Associated Ring Finger (C3HC4) 9 (MARCH9))
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别名
- MARCH9
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背景
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Synonyms: E3 ubiquitin protein ligase MARCH9, MARCH IX, Membrane associated RING CH protein IX, membrane associated ring finger C3HC4 9, Membrane associated RING finger protein 9, RING finger protein 179, RNF179, MARH9_HUMAN.
Background: Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction. The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s). MARCH9 (membrane-associated ring finger (C3HC4) 9), also known as RNF179, is a 346 amino acid multi-pass membrane protein that localizes to the golgi apparatus and contains one RING-CH-type zinc finger. Expressed ubiquitously, MARCH9 exists as a homodimer and functions as an E3 ubiquitin-protein ligase that accepts a ubiquitin residue from an E2 ubiquitin-conjugating enzyme and is thought to promote the degradation of target proteins, such as CD4 and MHC-I. Multiple isoforms of MARCH9 exist due to alternative splicing events.
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分子量
- 38kDa
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基因ID
- 92979
抗原
-
