Cullin 7 抗体 (PE)
Quick Overview for Cullin 7 抗体 (PE) (ABIN1434567)
抗原
See all Cullin 7 (CUL7) 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Cullin 7
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亚型
- IgG
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anti-Cullin 7 (CUL7) (C-Term) antibody
CUL7 适用: 人 WB, IP, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cullin 7 (CUL7) (AA 312-450) antibodyCUL7 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cullin 7 (CUL7) antibodyCUL7 适用: 人, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cullin 7 (CUL7) (AA 1-100) antibodyCUL7 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2G11 unconjugated
anti-Cullin 7 (CUL7) (C-Term) antibodyCUL7 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- Cullin 7 (CUL7)
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别名
- Cullin 7
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背景
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Synonyms: CUL-7, CUL7, CUL7_HUMAN, Cullin-7, dJ20C7.5, KIAA0076.
Background: Component of a probable SCF-like E3 ubiquitin-protein ligase complex, which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably plays a role in the degradation of proteins involved in endothelial proliferation and/or differentiation (By similarity). Seems not to promote polyubiquitination and proteasomal degradation of TP53. In vitro, complexes of CUL7 with either CUL9 or FBXW8 or TP53 contain E3 ubiquitin-protein ligase activity.Involvement in disease: Defects in CUL7 are the cause of 3M syndrome type 1 (3M1). An autosomal recessive disorder characterized by severe pre- and postnatal growth retardation, facial dysmorphism, large head circumference, and normal intelligence and endocrine function. Skeletal changes include long slender tubular bones and tall vertebral bodies.
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分子量
- 191kDa
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基因ID
- 9820
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途径
- ER-Nucleus Signaling
抗原
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