GABRE 抗体 (PE)
Quick Overview for GABRE 抗体 (PE) (ABIN1429630)
抗原
See all GABRE 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human GABARE/GABA Receptor Epsilon
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亚型
- IgG
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anti-gamma-aminobutyric Acid (GABA) A Receptor, epsilon (GABRE) (AA 237-286) antibody
GABRE 适用: 人, 小鼠, 豚鼠, 兔, 猴 WB, IHC (p), IHC 宿主: 兔 Polyclonal unconjugated
anti-gamma-aminobutyric Acid (GABA) A Receptor, epsilon (GABRE) (AA 1-100) antibodyGABRE 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1G11 unconjugated
anti-gamma-aminobutyric Acid (GABA) A Receptor, epsilon (GABRE) (AA 35-84) antibodyGABRE 适用: 人, 小鼠, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-gamma-aminobutyric Acid (GABA) A Receptor, epsilon (GABRE) (Middle Region) antibodyGABRE 适用: 人, 小鼠, 豚鼠, 兔, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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FCM: 1:20-100
Optimal working dilution should be determined by the investigator. -
说明
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Exitation/Emission: 480,565nm/578nm
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at 4 °C
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有效期
- 12 months
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- GABRE (gamma-aminobutyric Acid (GABA) A Receptor, epsilon (GABRE))
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背景
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GAD-65 and GAD-67, glutamate decarboxylases, function to catalyze the production of GABA (gamma-aminobutyric acid). In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl- conductance that inhibits neuronal firing. GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. Both GABAA and GABAC are ligand-gated ion channels, however, they are structurally and functionally distinct. Members of the GABAA receptor family include GABAA R Alpha 1-6, GABAA R Beta 1-3, GABAA R Gamma 1-3, GABAA R Delta, GABAA R Epsilon, GABAA R Zeta 1 and GABAA R Zeta 2. The GABAB family is composed of GABAB R1 Alpha and GABAB R1 Beta. GABA transporters have also been identified and include GABA T-1, GABA T-2 and GABA T-3 (also designated GAT-1, -2, and -3). The GABA transporters function to terminate GABA action.
Subcellular location: Extracellular
Synonyms: GABAA receptor epsilon, GABAA receptor subunit epsilon, Gabre, Gamma aminobutyric acid GABA A receptor epsilon, Gamma aminobutyric acid receptor subunit epsilon, Gamma-aminobutyric acid receptor subunit epsilon, GBRE_HUMAN. -
途径
- Synaptic Membrane
抗原
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