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Metabotropic Glutamate Receptor 1 抗体 (PE)

This anti-Metabotropic Glutamate Receptor 1 antibody is a 兔 多克隆 antibody detecting Metabotropic Glutamate Receptor 1 in . Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN1429290
发货至: 中国

Quick Overview for Metabotropic Glutamate Receptor 1 抗体 (PE) (ABIN1429290)

抗原

See all Metabotropic Glutamate Receptor 1 (GRM1) 抗体
Metabotropic Glutamate Receptor 1 (GRM1) (Glutamate Receptor, Metabotropic 1 (GRM1))

适用

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  • 42
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  • 1
  • 1
  • 1
  • 1
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  • 1
人, 小鼠, 大鼠

宿主

  • 74
  • 8
  • 1
  • 1

克隆类型

  • 69
  • 15
多克隆

标记

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  • 5
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  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Metabotropic Glutamate Receptor 1 antibody is conjugated to PE

应用范围

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  • 纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human MGLUR1A/Metabotropic Glutamate Receptor 1a

    亚型

    IgG
  • 说明

    Exitation/Emission: 480,565nm/578nm

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at 4°C

    有效期

    12 months
  • 抗原

    Metabotropic Glutamate Receptor 1 (GRM1) (Glutamate Receptor, Metabotropic 1 (GRM1))

    别名

    MGLUR1A

    背景

    L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Alternative splice variants of the GRM1 gene have been described but their full-length nature has not been determined.

    Subcellular location: Extracellular


    Synonyms: G protein coupled receptor family C group 1 member A, Glutamate receptor metabotropic 1 alpha, Glutamate receptor metabotropic 1, GPRC1A, GRM 1, GRM1 alpha, GRM1, GRM1A, Human metabotropic glutamate receptor 1 alpha mRNA complete cds, Metabotropic glutamate receptor 1 alpha, Metabotropic glutamate receptor 1, mGlu1, MGLUR1, MGLUR1A, mGluR1alpha.
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