SLITRK4 抗体 (PE)
Quick Overview for SLITRK4 抗体 (PE) (ABIN1429020)
抗原
See all SLITRK4 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human SLITRK4
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亚型
- IgG
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应用备注
- FCM(1:20-100)
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说明
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Exitation/Emission: 480,565nm/578nm
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at 4°C
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有效期
- 12 months
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- SLITRK4 (SLIT and NTRK-Like Family, Member 4 (SLITRK4))
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别名
- Slitrk4
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背景
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SLITRK family proteins are integral membrane proteins that have a C-terminal domain that is partially similar to TRK neurotrophin receptor proteins and two leucine-rich repeat (LRR) domains that are similar to those of SLIT proteins. SLITRK4 (SLIT and NTRK-like protein 4) is a 837 amino acid single-pass type I membrane protein that contains 18 LRR (leucine-rich) repeats and is expressed in neural tissues, specifically in the thalamus, hypothalamus, subventricular zone, CA3 region of the hippocampus and cortical plate. SLITRK4 may be upregulated in some astrocytic brain tumors such as glioblastomas, astrocytomas and primitive neuroectodermal tumors. As compared with its family member SLITRK2, SLITRK4 only weakly suppresses neurite outgrowth. A study using genome-wide transcriptional profiling suggested that the gene encoding SLITRK4, as well as the ARL5B and PLA2G7 genes, may be involved in the pathogenesis of preeclampsia.
Subcellular location: Extracellular
Synonyms: DKFZp547M2010, SLIK4_HUMAN, SLIT and NTRK like family member 4, SLIT and NTRK like protein 4, SLIT and NTRK-like protein 4, Slit and trk like 4 protein, Slit and trk like gene 4, SLITRK 4, SLITRK4.
抗原
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