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SLC5A3 抗体 (PE)

This anti-SLC5A3 antibody is a 兔 多克隆 antibody detecting SLC5A3 in FACS. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN1429005
发货至: 中国

Quick Overview for SLC5A3 抗体 (PE) (ABIN1429005)

抗原

See all SLC5A3 抗体
SLC5A3 (Solute Carrier Family 5 Member 3 (SLC5A3))

适用

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人, 小鼠, 大鼠

宿主

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  • 1

克隆类型

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  • 2
多克隆

标记

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This SLC5A3 antibody is conjugated to PE

应用范围

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Flow Cytometry (FACS)
  • 纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human SLC5A3/SMIT

    亚型

    IgG
  • 应用备注

    FCM(1:20-100)

    说明

    Exitation/Emission: 480,565nm/578nm

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at 4°C

    有效期

    12 months
  • 抗原

    SLC5A3 (Solute Carrier Family 5 Member 3 (SLC5A3))

    别名

    Slc5a3/Smit

    背景

    Myo-inositol is involved in many important aspects of cellular regulation including membrane structure, signal transduction and osmoregulation. It is taken up into cells by the sodium/myo-inositol cotransporter (SMIT). SMIT activity maintains intracellular concentrations of myo-inositol, it is upregulated in response to hypertonic stress. The human SMIT protein is encoded by the SLC5A3 gene, which maps to chromosome 21q22.12. It is expressed in many human tissues, such as brain, kidney and placenta. Specifically, SMIT is abundantly expressed throughout the whole brain and spinal cord in fetal rat, but is downregulated in adult rat brain with the exception of the choroid plexus, where SMIT expression remains high. In kidney, SMIT localizes to the baso-lateral membranes of the thick ascending limb of Henle (TAL) and the inner medullary collecting duct (IMCD). Impaired SMIT activity is implicated in the pathogenesis of diabetes and Down syndrome.

    Subcellular location: Extracellular


    Synonyms: Na+/myo inositol cotransporter, Na+/myo-inositol cotransporter, SC5A3_HUMAN, SLC5A3, SMIT, SMIT2, sodium/myo inositol cotransporter 1, Sodium/myo inositol cotransporter, Sodium/myo-inositol cotransporter, solute carrier family 5 inositol transporters, member 3, Solute carrier family 5 member 3.

    途径

    Inositol Metabolic Process
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