NOMO1 抗体 (PE)
Quick Overview for NOMO1 抗体 (PE) (ABIN1427260)
抗原
See all NOMO1 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human NOMO1
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亚型
- IgG
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应用备注
- FCM(1:20-100)
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说明
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Exitation/Emission: 480,565nm/578nm
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at 4°C
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有效期
- 12 months
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- NOMO1 (NODAL Modulator 1 (NOMO1))
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别名
- Nomo1
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背景
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Three highly similar proteins termed NOMO1, NOMO2 and NOMO3, are encoded by a gene mapping to a region of duplication on the p arm of human chromosome 16. All three NOMO proteins share similar functions and have been difficult to characterize individually. NOMO1 (Nodal modulator 1), also known as PM5, is a 1,222 amino acid highly conserved single-pass type I membrane protein expressed in colon tumor tissue and normal colonic mucosa. NOMO proteins are novel antagonists of Nodal signaling which interact with Nicalin to form a Nicalin-NOMO complex, and are rapidly degraded or stabilized by Nicalin. NOMO proteins were once considered candidates for the development of pseudoxanthoma elasticum (PXE), a heritable disorder of connective tissue, as the NOMO genes are located in close proximity to the gene responsible for PXE development (MRP6).
Subcellular location: Extracellular
Synonyms: Nodal modulator 1, NOMO 1, Nomo, NOMO1, NOMO1_HUMAN, PM5, pM5 protein, pM5 protein telomeric copy, NOMO1_HUMAN.
抗原
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