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NOMO1 抗体 (PE)

This anti-NOMO1 antibody is a 兔 多克隆 antibody detecting NOMO1 in FACS. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN1427260
发货至: 中国

Quick Overview for NOMO1 抗体 (PE) (ABIN1427260)

抗原

See all NOMO1 抗体
NOMO1 (NODAL Modulator 1 (NOMO1))

适用

  • 46
  • 7
  • 7
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
人, 大鼠, 小鼠

宿主

  • 46

克隆类型

  • 46
多克隆

标记

  • 18
  • 5
  • 4
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This NOMO1 antibody is conjugated to PE

应用范围

  • 21
  • 14
  • 13
  • 13
  • 13
  • 7
  • 4
  • 3
  • 3
  • 3
  • 3
  • 1
Flow Cytometry (FACS)
  • 纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human NOMO1

    亚型

    IgG
  • 应用备注

    FCM(1:20-100)

    说明

    Exitation/Emission: 480,565nm/578nm

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at 4°C

    有效期

    12 months
  • 抗原

    NOMO1 (NODAL Modulator 1 (NOMO1))

    别名

    Nomo1

    背景

    Three highly similar proteins termed NOMO1, NOMO2 and NOMO3, are encoded by a gene mapping to a region of duplication on the p arm of human chromosome 16. All three NOMO proteins share similar functions and have been difficult to characterize individually. NOMO1 (Nodal modulator 1), also known as PM5, is a 1,222 amino acid highly conserved single-pass type I membrane protein expressed in colon tumor tissue and normal colonic mucosa. NOMO proteins are novel antagonists of Nodal signaling which interact with Nicalin to form a Nicalin-NOMO complex, and are rapidly degraded or stabilized by Nicalin. NOMO proteins were once considered candidates for the development of pseudoxanthoma elasticum (PXE), a heritable disorder of connective tissue, as the NOMO genes are located in close proximity to the gene responsible for PXE development (MRP6).

    Subcellular location: Extracellular


    Synonyms: Nodal modulator 1, NOMO 1, Nomo, NOMO1, NOMO1_HUMAN, PM5, pM5 protein, pM5 protein telomeric copy, NOMO1_HUMAN.
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