LRRTM3 抗体 (AA 31-120) (PE)
Quick Overview for LRRTM3 抗体 (AA 31-120) (PE) (ABIN1427140)
抗原
See all LRRTM3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 31-120
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交叉反应
- 小鼠
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预测反应
- Human,Rat,Cow,Sheep,Pig,Chicken,Rabbit,Monkey
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human LRRTM3
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亚型
- IgG
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应用备注
- FCM 1:20-100
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- LRRTM3 (Leucine Rich Repeat Transmembrane Neuronal 3 (LRRTM3))
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别名
- LRRTM3
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背景
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Synonyms: Leucine rich repeat transmembrane neuronal protein 3, Leucine-rich repeat transmembrane neuronal protein 3, LRRT3_HUMAN, Lrrtm3, MGC131810, PRO1693, UNQ803.
Background: The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic Alpha/Beta horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. The LRRTM protein family plays a role in the regulation of various cellular events during nervous system development. Localizing predominantly to the nervous system, LRRTM family members are known to exhibit synaptogenic activity. LRRTM3 (leucine rich repeat transmembrane neuronal 3) is a 581 amino acid single-pass type I membrane protein belonging to the LRRTM family. LRRTM3 is involved in the development and maintenance of the vertebrate nervous system, and contains ten LRR repeats. Expressed in neuronal tissues, LRRTM3 is encoded by a gene that maps to a region of chromosome 10 that has been linked to late-onset Alzheimer disease and elevated plasma Beta-Amyloid. As a result of alternative splicing events, two LRRTM3 isoforms exist.
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途径
- Synaptic Membrane
抗原
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