FAT3 抗体 (PE)
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北京 101111
Quick Overview for FAT3 抗体 (PE) (ABIN1424720)
抗原
See all FAT3 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human CDHF15/FAT3
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亚型
- IgG
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anti-FAT Tumor Suppressor Homolog 3 (FAT3) (AA 1209-1470) antibody
FAT3 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- FCM(1:20-100)
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说明
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Exitation/Emission: 480,565nm/578nm
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at 4°C
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有效期
- 12 months
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- FAT3 (FAT Tumor Suppressor Homolog 3 (FAT3))
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别名
- Cdhf15/Fat3
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背景
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The cadherins represent a family of Ca2+-dependent adhesion molecules that function to mediate cell to cell binding that is critical for the maintenance of structure and morphogenesis. Cadherins each contain a large extracellular domain at the N-terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short C-terminal intracellular domain interacts with a variety of cytoplasmic proteins, including â^-catenin, to regulate cadherin function. The cadherin superfamily includes cadherins, protocadherins, desmogleins and desmocollins. FAT3 (FAT tumor suppressor homolog 3, also known as CDHF15 or CDHR10, is a 4,589 amino acid single-pass type I membrane protein expressed in ES cells, primitive neuroectoderm, fetal brain, infant brain, adult neural tissues and prostate. Containing thirty-three cadherin domains, four EGF-like domains and one laminin G-like domain, FAT3 may participate in the interactions between neurites derived from specific subsets of neurons during development.
Subcellular location: Extracellular
Synonyms: Cadherin family member 15, CDHF15, CDHR10, FAT tumor suppressor homolog 3, Fat3, FAT3_HUMAN, hFat3, Protocadherin Fat 3.
抗原
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