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FAT3 抗体 (PE)

This anti-FAT3 antibody (ABIN1424720) is a Rabbit Polyclonal antibody detecting FAT3 in FACS. Suitable for Human, Mouse, Rat.
产品编号 ABIN1424720
发货至: 中国

Quick Overview for FAT3 抗体 (PE) (ABIN1424720)

抗原

See all FAT3 抗体
FAT3 (FAT Tumor Suppressor Homolog 3 (FAT3))

适用

人, 小鼠, 大鼠

宿主

  • 28

克隆类型

  • 28
多克隆

标记

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This FAT3 antibody is conjugated to PE

应用范围

  • 13
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Flow Cytometry (FACS)
  • 纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human CDHF15/FAT3

    亚型

    IgG
  • 应用备注

    FCM(1:20-100)

    说明

    Exitation/Emission: 480,565nm/578nm

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at 4°C

    有效期

    12 months
  • 抗原

    FAT3 (FAT Tumor Suppressor Homolog 3 (FAT3))

    别名

    Cdhf15/Fat3

    背景

    The cadherins represent a family of Ca2+-dependent adhesion molecules that function to mediate cell to cell binding that is critical for the maintenance of structure and morphogenesis. Cadherins each contain a large extracellular domain at the N-terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short C-terminal intracellular domain interacts with a variety of cytoplasmic proteins, including â^-catenin, to regulate cadherin function. The cadherin superfamily includes cadherins, protocadherins, desmogleins and desmocollins. FAT3 (FAT tumor suppressor homolog 3, also known as CDHF15 or CDHR10, is a 4,589 amino acid single-pass type I membrane protein expressed in ES cells, primitive neuroectoderm, fetal brain, infant brain, adult neural tissues and prostate. Containing thirty-three cadherin domains, four EGF-like domains and one laminin G-like domain, FAT3 may participate in the interactions between neurites derived from specific subsets of neurons during development.

    Subcellular location: Extracellular


    Synonyms: Cadherin family member 15, CDHF15, CDHR10, FAT tumor suppressor homolog 3, Fat3, FAT3_HUMAN, hFat3, Protocadherin Fat 3.
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