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Transferrin Receptor 抗体 (PE-Cy7)

This anti-Transferrin Receptor antibody is a 兔 多克隆 antibody detecting Transferrin Receptor in FACS 和 WB. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN1423934
发货至: 中国

Quick Overview for Transferrin Receptor 抗体 (PE-Cy7) (ABIN1423934)

抗原

See all Transferrin Receptor (TFRC) 抗体
Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This Transferrin Receptor antibody is conjugated to PE-Cy7

应用范围

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Flow Cytometry (FACS), Western Blotting (WB)
  • 交叉反应

    人, 小鼠

    预测反应

    Rat,Dog,Cow,Pig,Horse,Guinea Pig

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human Transferrin receptor

    亚型

    IgG
  • 应用备注

    FCM(1:100-500)
    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

    别名

    Transferrin receptor

    背景

    Synonyms: T9, TR, TFR, p90, CD71, TFR1, TRFR, Transferrin receptor protein 1, TFRC

    Background: Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site.

    分子量

    74/85kDa

    基因ID

    7037

    UniProt

    P02786

    途径

    Transition Metal Ion Homeostasis
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