NDST1 抗体 (HRP)
Quick Overview for NDST1 抗体 (HRP) (ABIN1423144)
抗原
See all NDST1 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human NDST1
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亚型
- IgG
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应用备注
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WB 1:300-5000
IHC-P 1:200-400 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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注意事项
- Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- NDST1 (N-Deacetylase/N-Sulfotransferase (Heparan Glucosaminyl) 1 (NDST1))
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别名
- NDST1
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背景
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Synonyms: [Heparan sulfate]-glucosamine N-sulfotransferase 1, Bunctional heparan sulfate N-deacetylase/N-sulfotransferase 1, Glucosaminyl N-deacetylase/N-sulfotransferase 1, Heparan sulfate N-deacetylase 1, Heparan sulfate N-sulfotransferase 1, HSNST 1, HSNST-1, HSST, HSST1, N-heparan sulfate sulfotransferase 1, N-HSST 1, NDST-1, Ndst1, NDST1_HUMAN.
Background: Essential bifunctional enzyme that catalyzes both the N-deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA dissacharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Plays a role in determining the extent and pattern of sulfation of heparan sulfate. Compared to other NDST enzymes, its presence is absolutely required. Participates in biosynthesis of heparan sulfate that can ultimately serve as L-selectin ligands, thereby playing a role in inflammatory response.
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基因ID
- 3340
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途径
- Regulation of Systemic Arterial Blood Pressure by Hormones, Glycosaminoglycan Metabolic Process
抗原
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