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BRD4 抗体 (Cy3)

This anti-BRD4 antibody is a 兔 多克隆 antibody detecting BRD4 in WB 和 IF (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN1422365
发货至: 中国

Quick Overview for BRD4 抗体 (Cy3) (ABIN1422365)

抗原

See all BRD4 抗体
BRD4 (Bromodomain Containing 4 (BRD4))

适用

  • 95
  • 47
  • 33
  • 6
  • 5
  • 5
  • 5
  • 4
  • 2
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 90
  • 3
  • 2
  • 1

克隆类型

  • 70
  • 25
  • 1
多克隆

标记

  • 46
  • 8
  • 6
  • 6
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This BRD4 antibody is conjugated to Cy3

应用范围

  • 66
  • 37
  • 32
  • 26
  • 18
  • 17
  • 12
  • 9
  • 8
  • 8
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human Brd4/CAP

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    BRD4 (Bromodomain Containing 4 (BRD4))

    别名

    BRD4/CAP

    背景

    Synonyms: Brd4, BRD4_HUMAN, bromodomain containing protein 4, Bromodomain-containing protein 4, CAP, chromosome associated protein, HUNK1, Protein HUNK1.

    Background: Brd4 belongs to the BET family, a group of structurally related proteins containing two bromodomains. Through these two domains, Brd4 associates with mitotic chromosomes and its expression correlates with cell growth. Expression of Brd4 inhibits cell cycle progression from G(1) to S, due to binding to the largest subunit of replication factor C (RFC) to prevent DNA elongation. Altered Brd4 function correlates with poorly differentiated carcinoma, with aggresive phenotype and a highly lethal outcome.

    基因ID

    23476

    UniProt

    O60885

    途径

    Chromatin Binding, SARS-CoV-2 Protein Interactome
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