BIN2 抗体 (HRP)
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北京 101111
Quick Overview for BIN2 抗体 (HRP) (ABIN1422184)
抗原
See all BIN2 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human BIN2/BRAP1
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亚型
- IgG
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anti-Bridging Integrator 2 (BIN2) (AA 290-496) antibody
BIN2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Bridging Integrator 2 (BIN2) (AA 14-42), (N-Term) antibodyBIN2 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB27307 unconjugated
anti-Bridging Integrator 2 (BIN2) (AA 1-239) antibodyBIN2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Bridging Integrator 2 (BIN2) (AA 359-408) antibodyBIN2 适用: 人, Cow, Pig, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Bridging Integrator 2 (BIN2) (AA 1-244) antibodyBIN2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Bridging Integrator 2 (BIN2) (Middle Region) antibodyBIN2 适用: 人, 大鼠, Cow, Pig, 兔, 犬, 马 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
IHC-P 1:200-400 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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注意事项
- Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- BIN2 (Bridging Integrator 2 (BIN2))
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别名
- BIN2
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背景
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Synonyms: BIN2, BIN2_HUMAN, BRAP 1, Breast cancer associated protein BRAP1, Breast cancer-associated protein 1, Bridging integrator 2.
Background: BAR proteins are characterized by a common N-terminal BAR (bin, amphiphysin and Rvs161/167) domain and are recognized as adaptor proteins that are involved in many cellular processes. BIN1 and BIN2 are BAR proteins that share 61 % sequence similarity. BIN1 (Bridging integrator 1) is a ubiquitously expressed regulatory protein for synaptic vesicle endocytosis. BIN1 also interacts with the transcription factors c-Myc and MyoD, potentially functioning as a tumor suppressor. BIN2, also known as Breast cancer-associated protein 1, is a 565 amino acid protein that interacts with BIN1. In contrast to BIN1, BIN2 lacks tumor suppressor features as well as a c-Myc interacting region. BIN2 shows preferred expression in tissues of hematopoietic origin, with high levels found in spleen, thymus, colon, placenta, lymphoid and granulocytic cells. There are two isoforms of BIN2 that are produced as a result of alternative splicing events.
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基因ID
- 51411
抗原
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