FEZ1 抗体 (HRP)
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北京 101111
Quick Overview for FEZ1 抗体 (HRP) (ABIN1422160)
抗原
See all FEZ1 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human FEZ1
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亚型
- IgG
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anti-Fasciculation and Elongation Protein zeta 1 (Zygin I) (FEZ1) (Internal Region) antibody
Verified FEZ1 适用: 人, 大鼠 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Fasciculation and Elongation Protein zeta 1 (Zygin I) (FEZ1) (AA 1-392) antibodyFEZ1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Fasciculation and Elongation Protein zeta 1 (Zygin I) (FEZ1) (AA 12-200) antibodyFEZ1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Fasciculation and Elongation Protein zeta 1 (Zygin I) (FEZ1) (AA 1-392) antibodyFEZ1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
IHC-P 1:200-400 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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注意事项
- Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- FEZ1 (Fasciculation and Elongation Protein zeta 1 (Zygin I) (FEZ1))
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别名
- FEZ1
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背景
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Synonyms: Fasciculation and elongation protein zeta 1, Fasciculation and elongation protein zeta-1, Fez 1, Fez, Fez-like zinc finger protein, FEZ1, FEZ1_HUMAN, Fezl, Forebrain embryonic zinc-finger like protein, Zpf312, Zygin 1, Zygin I, Zygin-1, Zygin1, ZyginI.
Background: Frequent loss of heterozygosity (LOH) at human chromosome 8p22-p21 is associated with various tumors including prostate and breast cancer. The 8p22-p21 region contains the FEZ1 gene, which is altered in tumors of the esophagus, prostate and breast. The FEZ1 protein (also known as leucine zipper putative tumor suppressor or LZTS1) contains a DNA-binding leucine zipper motif. FEZ1 is expressed in normal breast and prostate, but alterations in FEZ1 expression result in abnormal cell growth. The absence of FEZ1 expression is characteristic of breast and prostate cancer cell lines as well as primary breast and pro-state tumors. This absence of FEZ1 may be due to several factors, including mutations in the FEZ1 gene or hypermethylation of the CpG island flanking the FEZ1 promoter region. FEZ1 acts as a negative regulator of cell growth. During cell-cycle progression, FEZ1 localizes to microtubule components and is hyperphosphorylated by cAMP-dependent kinase.
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基因ID
- 9638
抗原
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