JMJD7 抗体 (Cy5)
Quick Overview for JMJD7 抗体 (Cy5) (ABIN1420866)
抗原
See all JMJD7 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human JMJD7
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亚型
- IgG
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anti-Jumonji Domain Containing 7 (JMJD7) (AA 179-228) antibody
JMJD7 适用: 人, 小鼠, 大鼠, 犬, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-Jumonji Domain Containing 7 (JMJD7) (AA 1-316) antibodyJMJD7 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Jumonji Domain Containing 7 (JMJD7) (C-Term) antibodyJMJD7 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- IF(IHC-P) 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- JMJD7 (Jumonji Domain Containing 7 (JMJD7))
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别名
- JMJD7
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背景
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Synonyms: JmjC domain-containing protein 7, JMJD7, JMJD7_HUMAN, Jumonji domain containing 7, Jumonji domain-containing protein 7.
Background: A crucial regulator of chromatin dynamics and DNA transcription is the covalent modification and methylation of histones. Generally, methylation of certain lysine residues on Histone H3 and Histone H4 can be associated with transcriptionally active or inactive chromatin. This regulation has profound effects on the expression of genes and is part of an epigenetic memory network that determines cell fate. JMJD7 (Jumonji domain-containing protein 7) is a member of a family of JMJC domain-containing histone demethylases that are directly involved in removing methyl residues from distinct and unique lysine residues. These actions are implicated in gene expression and the regulation of cell senescence. JMJC domain-containing histone demethylases are also likely involved in development via their ability to regulate gene expression. JMJD7 contains one JMJC domain and was originally thought to be an alternatively spliced isoform of PLA2G4B.
抗原
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