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TRIM8 抗体 (Cy5)

This anti-TRIM8 antibody is a 兔 多克隆 antibody detecting TRIM8 in WB 和 IF (p). Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN1420548
发货至: 中国

Quick Overview for TRIM8 抗体 (Cy5) (ABIN1420548)

抗原

See all TRIM8 抗体
TRIM8 (Tripartite Motif Containing 8 (TRIM8))

适用

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  • 1
人, 大鼠, 小鼠

宿主

  • 32
  • 12
  • 1

克隆类型

  • 35
  • 10
多克隆

标记

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This TRIM8 antibody is conjugated to Cy5

应用范围

  • 33
  • 15
  • 12
  • 11
  • 11
  • 6
  • 4
  • 2
  • 1
Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human TRIM8/RNF27

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    TRIM8 (Tripartite Motif Containing 8 (TRIM8))

    别名

    RNF27

    背景

    Synonyms: Lioblastoma expressed ring finger protein, Ring finger protein 27, RNF27, RP11-47A8.4, TRIM8, Tripartite mot containing 8, Tripartite mot protein TRIM8, TRIM8_HUMAN.

    Background: The tripartite motif (TRIM) family of proteins are characterized by a conserved TRIM domain that includes a coiled-coil region, a B-box type zinc finger, one RING finger and three zinc-binding domains. TRIM8 (tripartite motif containing 8), also known as GERP (glioblastoma-expressed RING finger protein) or RNF27 (RING finger protein 27), is a 551 amino acid protein that is thought to function as an E3 ubiquitin-protein ligase that promotes SOCS-1 proteasomal degradation. As a widely expressed homodimer, TRIM8 localizes to nuclear bodies and contains two B box-type zinc fingers and one RING-type zinc finger. TRIM8 is expressed in lung, heart, brain and skeletal muscle, with low levels detected in intestine, placenta, leukocytes and liver. The gene encoding TRIM8 maps to human chromosome 10q24.32.

    基因ID

    81603

    UniProt

    Q9BZR9
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