CHAF1A 抗体 (HRP)
Quick Overview for CHAF1A 抗体 (HRP) (ABIN1420318)
抗原
See all CHAF1A 抗体适用
宿主
克隆类型
标记
应用范围
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    - 
                                            交叉反应
- 人, 小鼠, 大鼠
- 
                                            纯化方法
- Purified by Protein A.
- 
                                            免疫原
- KLH conjugated synthetic peptide derived from human p150 CAF1
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                                            亚型
- IgG
 
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                                            应用备注
- 
                        WB 1:300-5000
 IHC-P 1:200-400
- 
                                            限制
- 仅限研究用
 
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    - 
                                            状态
- Liquid
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                                            浓度
- 1 μg/μL
- 
                                            缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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                                            储存液
- ProClin
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                                            注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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                                            注意事项
- Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
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                                            储存条件
- -20 °C
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                                            储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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                                            有效期
- 12 months
 
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    - CHAF1A (Chromatin Assembly Factor 1, Subunit A (p150) (CHAF1A))
- 
                                            别名
- p150 CAF1
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                                            背景
- 
                        Synonyms: CAF-1 p150, CAF 1 150 kDa subunit, CAF 1, CAF 1 subunit A, CAF, CAF I 150 kDa subunit, CAF I p150, CAF Ip150, CAF-1 subunit A, CAF-I 150 kDa subunit, CAF-I p150, CAF1 150 kDa subunit, CAF1, CAF1 p150 Subunit, CAF1 subunit A, CAF1A, CAF1A, CAF1A_HUMAN, CAF1B, CAF1P150, CAF1P155, CAF1P155, CHAF1A, Chromatin assembly factor 1 subunit A, Chromatin Assembly Factor 1 Subunit A p150, Chromatin assembly factor I 150 kDa, Chromatin assembly factor I 150 kDa, Chromatin Assembly Factor I, Chromatin assembly factor I p150 subunit, DCAF1, hp150, Nucleosome Remodeling Factor 150 kDa Subunit, NURF150, P150. Background: Core component of the CAF-1 complex, a complex thought to mediate chromatin assembly in DNA replication and DNA repair. Assembles histone octamers onto replicating DNA in vitro. CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA, histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer. CHAF1A binds to histones H3 and H4. It may play a role in heterochromatin maintenance in proliferating cells by bringing newly synthesized cbx proteins to heterochromatic DNA replication foci (By similarity). The CCR4-NOT complex functions as general transcription regulation complex. Also involved in vitamin D-coupled transcription regulation via its association with the WINAC complex, a chromatin-remodeling complex recruited by vitamin D receptor (VDR), which is required for the ligand-bound VDR-mediated transrepression of the CYP27B1 gene. 
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                                            基因ID
- 10036
 抗原
- 
                    
 
                                     
                                     
                                    