MID1 抗体 (AA 200-250) (Cy3)
Quick Overview for MID1 抗体 (AA 200-250) (Cy3) (ABIN1420253)
抗原
See all MID1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 200-250
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Midline-1/RNF59
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亚型
- IgG
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anti-Midline 1 (MID1) (N-Term) antibody
MID1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Midline 1 (MID1) (N-Term) antibodyMID1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Midline 1 (MID1) (AA 478-667) antibodyMID1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Midline 1 (MID1) (AA 441-540) antibodyMID1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2C11 unconjugated
anti-Midline 1 (MID1) (N-Term) antibodyMID1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Midline 1 (MID1) (N-Term) antibodyMID1 适用: 人, 小鼠, 大鼠, 犬, 猴 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Midline 1 (MID1) (AA 71-120) antibodyMID1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Midline 1 (MID1) (AA 441-540) antibodyMID1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Midline 1 (MID1) (AA 465-514) antibodyMID1 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 斑马鱼, 猴, Pig, Bat, 小鸡, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Midline 1 (MID1) (AA 1-212) antibodyMID1 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
- IF(IHC-P) 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- MID1 (Midline 1 (MID1))
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别名
- Midline-1
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背景
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Synonyms: BBBG1, Finger on X and Y mouse homolog of antibody, FXY, GBBB1, MID-1, Mid1, Midin, Midline 1 Opitz/BBB syndrome, Midline 1, Midline 1 ring finger, Midline 1 RING finger protein, Midline-1, Midline1, OGS1, OSX, Putative transcription factor XPRF, RING finger protein 59, RNF59, TRI18, TRI18_HUMAN, TRIM18, Tripartite mot containing protein 18, Tripartite mot protein TRIM18, Tripartite mot-containing protein 18, XPRF, Zinc finger X and Y antibody, ZNFXY.
Background: Midline-1 (Tripartite motif-containing protein 18, Putative transcription factor XPRF, RING finger protein 59) is a 667 amino acid protein encoded by the human gene MID1. Midline-1 belongs to the TRIM/RBCC family and contains two B box-type zinc fingers, one B30.2/SPRY domain, one COS domain, one fibronectin type-III domain and one RING-type zinc finger. Midline-1 is believed to have E3 ubiquitin ligase activity which targets the catalytic subunit of protein phosphatase 2 for degradation. It is a cytoplasmic protein found as a homodimer or heterodimer with Midline-2. It also interacts with IGBP1 (Lymphocyte signaling protein A4). Defects in MID1 are the cause of Opitz syndrome type I (OS-I). OS-I is an X-linked recessive disorder characterized by hypertelorism, genital-urinary defects such as hypospadias in males and splayed labia in females, lip-palate-laryngotracheal clefts, imperforate anus, developmental delay and congenital heart defects. OS-I mutations produce proteins with a decreased affinity for microtubules.
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基因ID
- 4281
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UniProt
- O15344
抗原
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