PJA2 抗体 (AA 420-470) (Cy5)
Quick Overview for PJA2 抗体 (AA 420-470) (Cy5) (ABIN1419732)
抗原
See all PJA2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 420-470
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human PJA2/RNF131
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亚型
- IgG
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应用备注
- IF(IHC-P) 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- PJA2 (Praja Ring Finger 2 (PJA2))
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别名
- RNF131
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背景
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Synonyms: E3 ubiquitin protein ligase Praja2, E3 ubiquitin-protein ligase Praja-2, KIAA0438, Neurodap 1, Neurodap1, PJA 2, PJA2, PJA2_HUMAN, Praja 2, Praja 2 RING H2 mot containing, praja ring finger 2, Praja ring finger 2 E3 ubiquitin protein ligase, Praja2, RING finger protein 131, RNF 131, RNF131.
Background: PJA2, also known as E3 ubiquitin-protein ligase praja-2, RNF131 (ring finger protein 131) or Neurodap1, is a 708 amino acid protein that contains one ring-type zinc finger and exists as two alternatively spliced isoforms. Significantly conserved in chimpanzee, dog, cow, mouse, rat, chicken and zebrafish, PJA2 shares 52 % identity with PJA1, which is involved in protein ubiquitination in brain and may play a role in X-linked mental retardation. Encoded by a gene that maps to human chromosome 5q21.3, PJA2 localizes to both endoplasmic reticulum and Golgi apparatus membranes. Participating in E2-dependent, E3 ubiquitin-protein ligase activity, PJA2 binds to a variety of E2s and interacts with ubiquitin-conjugating enzymes, such as UBE2D2, in vitro.
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基因ID
- 9867
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UniProt
- O43164
抗原
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