PJA2 抗体 (AA 420-470) (Cy3)
Quick Overview for PJA2 抗体 (AA 420-470) (Cy3) (ABIN1419731)
抗原
See all PJA2 抗体适用
宿主
克隆类型
标记
应用范围
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    - 
                                            抗原表位
- AA 420-470
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                                            交叉反应
- 人, 小鼠, 大鼠
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                                            纯化方法
- Purified by Protein A.
- 
                                            免疫原
- KLH conjugated synthetic peptide derived from human PJA2/RNF131
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                                            亚型
- IgG
 
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                                            应用备注
- IF(IHC-P) 1:50-200
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                                            限制
- 仅限研究用
 
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    - 
                                            状态
- Liquid
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                                            浓度
- 1 μg/μL
- 
                                            缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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                                            储存液
- ProClin
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                                            注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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                                            储存条件
- -20 °C
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                                            储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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                                            有效期
- 12 months
 
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    - PJA2 (Praja Ring Finger 2 (PJA2))
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                                            别名
- RNF131
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                                            背景
- 
                        Synonyms: E3 ubiquitin protein ligase Praja2, E3 ubiquitin-protein ligase Praja-2, KIAA0438, Neurodap 1, Neurodap1, PJA 2, PJA2, PJA2_HUMAN, Praja 2, Praja 2 RING H2 mot containing, praja ring finger 2, Praja ring finger 2 E3 ubiquitin protein ligase, Praja2, RING finger protein 131, RNF 131, RNF131. Background: PJA2, also known as E3 ubiquitin-protein ligase praja-2, RNF131 (ring finger protein 131) or Neurodap1, is a 708 amino acid protein that contains one ring-type zinc finger and exists as two alternatively spliced isoforms. Significantly conserved in chimpanzee, dog, cow, mouse, rat, chicken and zebrafish, PJA2 shares 52 % identity with PJA1, which is involved in protein ubiquitination in brain and may play a role in X-linked mental retardation. Encoded by a gene that maps to human chromosome 5q21.3, PJA2 localizes to both endoplasmic reticulum and Golgi apparatus membranes. Participating in E2-dependent, E3 ubiquitin-protein ligase activity, PJA2 binds to a variety of E2s and interacts with ubiquitin-conjugating enzymes, such as UBE2D2, in vitro. 
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                                            基因ID
- 9867
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                                            UniProt
- O43164
 抗原
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