RNF31 抗体 (HRP)
Quick Overview for RNF31 抗体 (HRP) (ABIN1419538)
抗原
See all RNF31 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human RNF31
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亚型
- IgG
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anti-Ring Finger Protein 31 (RNF31) (Middle Region) antibody
RNF31 适用: 人, 小鼠, 大鼠, 兔, 犬, 豚鼠, 马, Cow WB 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 31 (RNF31) (AA 955-983), (C-Term) antibodyRNF31 适用: 人 WB 宿主: 兔 Polyclonal RB39346 unconjugated
anti-Ring Finger Protein 31 (RNF31) (AA 421-700) antibodyRNF31 适用: 人 ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 31 (RNF31) (C-Term) antibodyVerified RNF31 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Ring Finger Protein 31 (RNF31) antibodyRNF31 适用: 人, 小鼠, 大鼠 WB, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 31 (RNF31) (C-Term) antibodyRNF31 适用: 人, 兔, 豚鼠, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 31 (RNF31) (AA 500-700) antibodyRNF31 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
IHC-P 1:200-400 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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注意事项
- Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- RNF31 (Ring Finger Protein 31 (RNF31))
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别名
- RNF31
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背景
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Synonyms: HOIP, ZIBRA, E3 ubiquitin-protein ligase RNF31, HOIL-1-interacting protein, RING finger protein 31, Zinc in-between-RING-finger ubiquitin-associated domain protein, RNF31
Background: E3 ubiquitin-protein ligase component of the LUBAC complex which conjugates linear ('Met-1'-linked) polyubiquitin chains to substrates and plays a key role in NF-kappa-B activation and regulation of inflammation. LUBAC conjugates linear polyubiquitin to IKBKG and RIPK1 and is involved in activation of the canonical NF-kappa-B and the JNK signaling pathways. Linear ubiquitination mediated by the LUBAC complex interferes with TNF-induced cell death and thereby prevents inflammation. LUBAC is proposed to be recruited to the TNF-R1 signaling complex (TNF-RSC) following polyubiquitination of TNF-RSC components by BIRC2 and/or BIRC3 and to conjugate linear polyubiquitin to IKBKG and possibly other components contributing to the stability of the complex. Together with FAM105B/otulin, the LUBAC complex regulates the canonical Wnt signaling during angiogenesis. Binds polyubiquitin of different linkage types.
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基因ID
- 55072
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UniProt
- Q96EP0
抗原
-
