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VGLL2 抗体 (HRP)

This anti-VGLL2 antibody is a 兔 多克隆 antibody detecting VGLL2 in WB 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN1419190
发货至: 中国

Quick Overview for VGLL2 抗体 (HRP) (ABIN1419190)

抗原

See all VGLL2 抗体
VGLL2 (Vestigial Like 2 (VGLL2))

适用

  • 46
  • 32
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  • 7
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  • 1
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人, 小鼠, 大鼠

宿主

  • 45
  • 2

克隆类型

  • 47
多克隆

标记

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  • 2
  • 1
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  • 1
  • 1
  • 1
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This VGLL2 antibody is conjugated to HRP

应用范围

  • 36
  • 13
  • 13
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human VGLL2

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    IHC-P 1:200-400

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    注意事项

    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    VGLL2 (Vestigial Like 2 (VGLL2))

    别名

    VGLL2

    背景

    Synonyms: Protein VITO1, Transcription cofactor vestigial like 2, Transcription cofactor vestigial like protein 2, Transcription cofactor vestigial-like protein 2, Vestigial like 2, Vestigial like 2 Drosophila, Vgl-2, VGL2, VGLL 2, Vgll2, VGLL2_HUMAN, VITO1.

    Background: Vgl-2, also known as VITO-1, is a 317 amino acid protein that contains a domain through which it interacts with TEF-1, a protein that plays a role in controlling the expression of numerous genes. Specific to skeletal muscle, Vgl-2 is expressed highly in adult fast muscle and is expressed at lower levels in adult slow muscle and fetal skeletal muscle. During muscle differentiation, Vgl-2 mRNA levels increase and Vgl-2 translocates from the cytoplasm to the nucleus. Overexpression of Vgl-2 in MYOD-transfected 10T1/2 mouse embryonic fibroblasts increases expression of myosin heavy chain (MHC), which is a marker of terminal muscle differentiation. This evidence suggests that Vgl-2 is essential for muscle gene expression. There are two isoforms of Vgl-2 that are produced as a result of alternative splicing events.

    基因ID

    245806
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