BAGE2 抗体 (HRP)
Our Local Distributor
北京 101111
Quick Overview for BAGE2 抗体 (HRP) (ABIN1418788)
抗原
适用
宿主
克隆类型
标记
应用范围
-
-
交叉反应
- 人
-
纯化方法
- Purified by Protein A.
-
免疫原
- KLH conjugated synthetic peptide derived from human BAGE2
-
亚型
- IgG
-
-
anti-B Melanoma Antigen Family, Member 2 (BAGE2) antibody
BAGE2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- IHC-P 1:200-400
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
注意事项
- Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
-
有效期
- 12 months
-
-
- BAGE2 (B Melanoma Antigen Family, Member 2 (BAGE2))
-
别名
- BAGE2
-
背景
-
Synonyms: B melanoma antigen 2, B melanoma antigen family, member 2, Cancer/testis antigen 2.2, CT2.2, BAGE2_HUMAN.
Background: Members of the BAGE gene family encode antigens that are recognized by cytotoxic T lymphocytes and are also known as CT (cancer/testis) antigens. Generated by juxtacentromeric shuffling of the MLL3 gene, the ancestral BAGE gene was expanded by acrocentric exchanges and/or juxtacentromeric movements.Generally, BAGE proteins are silent in all normal tissues with the exception of testis. BAGE2 and BAGE 3 (B melanoma antigen 2 and 3, respectively), also known as Cancer/testis antigen 2.2 and 2.3 (respectively), are 109 amino acid secreted proteins that are expressed in 22 % of melanomas, lung and bladder carcinomas, and are also expressed in normal testis tissue. Like the genes encoding MAGE proteins, BAGE genes are most likely silenced by DNA methylation and/or chromatin compaction in normal tissues other than testis.
抗原
-
