DIS3L 抗体 (Cy3)
Quick Overview for DIS3L 抗体 (Cy3) (ABIN1418423)
抗原
See all DIS3L 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human DIS3L
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亚型
- IgG
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anti-DIS3-Like Exonuclease 1 (DIS3L) (AA 1-300) antibody
DIS3L 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-DIS3-Like Exonuclease 1 (DIS3L) (AA 1-971) antibodyDIS3L 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-DIS3-Like Exonuclease 1 (DIS3L) (AA 1-971) antibodyDIS3L 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-DIS3-Like Exonuclease 1 (DIS3L) (AA 195-224), (N-Term) antibodyDIS3L 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB27115 unconjugated
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应用备注
- IF(IHC-P) 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- DIS3L (DIS3-Like Exonuclease 1 (DIS3L))
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别名
- DIS3L
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背景
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Synonyms: DIS3 like exonuclease 1, DIS3 mitotic control homolog S. cerevisiae like, FLJ38088, KIAA1955, MGC4562, DI3L1_HUMAN.
Background: The exosome is a multi-protein complex composed of several highly conserved subunits, some of which are 3? to 5? exoribonucleases. The complex is involved in a variety of cellular processes and is responsible for degrading unstable mRNAs that contain AU-rich elements (AREs) in their untranslated 3? regions. DIS3, also known as RRP44, is a 958 amino acid protein that localizes to both the cytoplasm and the nucleus and contains one PINc domain. Widely expressed with highest expression in testis, DIS3 functions as a component of the exosome exoribonuclease complex and is required for processing of 7S pre-RNA into a mature nuclear complex and, ultimately, for proper mitotic progression. Abnormal expression levels of DIS3 may be associated with colon cancer, suggesting a role for DIS3 in tumorigenesis. Multiple isoforms of DIS3 exist due to alternative splicing events.
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基因ID
- 115752
抗原
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