MMS19 抗体 (AA 851-950) (Cy5)
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Quick Overview for MMS19 抗体 (AA 851-950) (Cy5) (ABIN1417968)
抗原
See all MMS19 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 851-950
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交叉反应
- 人, 小鼠
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预测反应
- Rat,Dog,Pig,Horse,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human MMS 19
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亚型
- IgG
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anti-MMS19 Nucleotide Excision Repair Homolog (MMS19) (AA 1-293) antibody
MMS19 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-MMS19 Nucleotide Excision Repair Homolog (MMS19) (AA 851-950) antibodyMMS19 适用: 人, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-MMS19 Nucleotide Excision Repair Homolog (MMS19) (Internal Region) antibodyMMS19 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- MMS19 (MMS19 Nucleotide Excision Repair Homolog (MMS19))
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别名
- MMS19
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背景
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Synonyms: MET18, MMS19L, hMMS19, MMS19 nucleotide excision repair protein homolog, MET18 homolog, MMS19-like protein, MMS19
Background: Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins such as ERCC2/XPD, FANCJ and RTEL1, thereby playing a key role in nucleotide excision repair (NER) and RNA polymerase II (POL II) transcription. As part of the mitotic spindle-associated MMXD complex, plays a role in chromosome segregation, probably by facilitating iron-sulfur cluster assembly into ERCC2/XPD. Indirectly acts as a transcriptional coactivator of estrogen receptor (ER), via its role in iron-sulfur insertion into some component of the TFIIH-machinery.
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基因ID
- 64210
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UniProt
- Q96T76
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途径
- Nuclear Hormone Receptor Binding
抗原
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