HOXD9 抗体 (AA 251-352) (Cy3)
Quick Overview for HOXD9 抗体 (AA 251-352) (Cy3) (ABIN1417841)
抗原
See all HOXD9 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 251-352
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预测反应
- Human,Mouse,Rat,Dog,Cow,Pig,Chicken,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human HOXD9
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亚型
- IgG
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anti-Homeobox D9 (HOXD9) (AA 38-276) antibody
HOXD9 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Homeobox D9 (HOXD9) (AA 146-210) antibodyHOXD9 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2A9 unconjugated
anti-Homeobox D9 (HOXD9) (AA 100-200) antibodyHOXD9 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Homeobox D9 (HOXD9) antibodyHOXD9 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Homeobox D9 (HOXD9) (N-Term) antibodyHOXD9 适用: 人, 大鼠, 豚鼠, Cow, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Homeobox D9 (HOXD9) (AA 143-192) antibodyHOXD9 适用: 人, 小鼠, 大鼠, 兔, 豚鼠, 小鸡, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Homeobox D9 (HOXD9) (AA 125-152) antibodyHOXD9 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB37125 unconjugated
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- HOXD9 (Homeobox D9 (HOXD9))
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别名
- HOXD9
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背景
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Synonyms: homeobox D9, Homeobox protein Hox D9, Hox 4.3, Hox 5.2, HOX4, HOX4C, RP23 313J15.10, HXD9_HUMAN.
Background: The Hox proteins play a role in patterns of embryonic development and cellular differentiation by regulating downstream target genes. In vivo, the HoxD9 protein interacts with the autoregulatory and cross-regulatory enhancers of the murine HoxB1 and human HoxD9 genes. Specifically, the HoxD9 protein interacts with the human control region (HCR) of the HoxD9 gene, thus inducing transcription of the HoxD9 promoter. HoxD9 may be a multifunctional transcriptional regulator, as it contains different activation domains. Activation of HoxD9 depends on the structure of the target regulatory element, and results in differential cofactor interaction. The HoxD9 protein is expressed in the early stages of mouse joint development, primarily in the articular cartilage. HoxD9 transcripts are also detected in the synovial tissue of arthritic mice, but not in that of normal mice, suggesting that HoxD9 may have a role in the pathology of arthritis. Furthermore, the HoxD9 protein is highly expressed in the synoviocytes of patients with rheumatoid arthritis (RA), but not in osteoarthritis patients. The human HoxD9 protein is also differentially expressed in the human cervical cancer cell line HeLa, but is not expressed in the normal cervix and may thus play a role in tumorigenesis.
抗原
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