FBXL21 抗体 (AA 121-220) (Cy7)
Quick Overview for FBXL21 抗体 (AA 121-220) (Cy7) (ABIN1417184)
抗原
See all FBXL21 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 121-220
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交叉反应
- 小鼠
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预测反应
- Human,Rat,Dog,Cow,Sheep
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human FBXL21/FBL3B
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亚型
- IgG
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- FBXL21 (F-Box and Leucine-Rich Repeat Protein 21 (FBXL21))
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别名
- FBXL21
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背景
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Synonyms: F box and leucine rich repeat protein 21, F box and leucine rich repeat protein 3 pseudogene, F box and leucine rich repeat protein 3B, F box protein Fbl3b, F box/LRR repeat protein 21, F box/LRR repeat protein 3B, Fbl 21, FBXL 21, FBXL-21, FBL 3, FBL 3B, Fbl21, FBL3, FBL-3B, FBL 3B, FBL3B, FBXL 21, FBXL 3B, FBXL 3P, FBXL3B, FBXL3P, MGC120237, FXL21_HUMAN.
Background: FBL3B is a 434 amino acid protein encoded by the human gene FBXL21. FBL3B contains one 40 amino acid F-box region, making it a member of the F-box family. FBL3B also contains three LRR (leucine-rich) repeats. F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein) type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination. F-box proteins are members of a large family that regulates cell cycle, immune response, signaling cascades and developmental programs by targeting proteins, such as cyclins, cyclin-dependent kinase inhibitors, IkB-a and b-catenin, for degradation by the proteasome after ubiquitination. FBL3B is a substrate-recognition component of the SCF complex that interacts with Skp1 p19 and CUL-1. FBL3B is also associated with expression and regulation of circadian and cryptochrome proteins.
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基因ID
- 26223
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途径
- Photoperiodism
抗原
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