FBXL5 抗体 (AA 31-130) (Cy7)
Quick Overview for FBXL5 抗体 (AA 31-130) (Cy7) (ABIN1417136)
抗原
See all FBXL5 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 31-130
-
交叉反应
- 人
-
预测反应
- Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
-
纯化方法
- Purified by Protein A.
-
免疫原
- KLH conjugated synthetic peptide derived from human FBXL5
-
亚型
- IgG
-
-
-
-
应用备注
- FCM 1:20-100
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
-
有效期
- 12 months
-
-
- FBXL5 (F-Box and Leucine-Rich Repeat Protein 5 (FBXL5))
-
别名
- FBXL5
-
背景
-
Synonyms: F box and leucine rich repeat protein 5, F box/LRR repeat protein 5, F-box and leucine-rich repeat protein 5, F-box protein FBL4/FBL5, F-box/LRR-repeat protein 5, FBL4, FBL5, FBXL5, FBXL5_HUMAN, FLR1, p45SKP2 like protein, p45SKP2-like protein.
Background: Component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in iron homeostasis by promoting the ubiquitination and subsequent degradation of IREB2/IRP2. Upon high iron and oxygen level, it specifically recognizes and binds IREB2/IRP2, promoting its ubiquitination and degradation by the proteasome. Promotes ubiquitination and subsequent degradation of DCTN1/p150-glued.
-
基因ID
- 26234
-
途径
- Transition Metal Ion Homeostasis
抗原
-