GLIPR2 抗体 (AA 51-154) (Cy5)
Quick Overview for GLIPR2 抗体 (AA 51-154) (Cy5) (ABIN1416798)
抗原
See all GLIPR2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 51-154
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预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human GLIPR2
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亚型
- IgG
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- GLIPR2 (GLI Pathogenesis-Related 2 (GLIPR2))
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别名
- GLIPR2
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背景
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Synonyms: GAPR 1, GAPR-1, GAPR1_HUMAN, GLI pathogenesis related 2, Glioma pathogenesis related protein 2, Glioma pathogenesis-related protein 2, GliPR 2, GLIPR2, Golgi associated plant pathogenesis related protein 1, Golgi associated PR 1 protein, Golgi-associated plant pathogenesis-related protein 1, Golgi-associated PR-1 protein, OTTMUSP00000007558, RP11-421H8.5, RP23-209M8.2, C77180, 5730414A08Rik, C9orf19.
Background: Cysteine-rich secretory proteins (CRISPs) represent a family of evolutionarily conserved proteins that may play a role in the innate immune system and are transcriptionally regulated by androgens in several tissues. GAPR-1 (Golgi-associated plant pathogenesis-related protein 1), also known as GLIPR2, is a 154 amino acid lipid anchor protein belonging to the CRISP family. GAPR-1 also shares similarity with the pathogenesis-related protein (PR) superfamily, and may play an important role in the immune system. Existing as a homodimer, GAPR-1 is highly expressed in lung and peripheral leukocytes with minor expression in liver and kidney. Containing a conserved sperm-coating protein (SCP) domain, GAPR-1 binds to negatively charged lipids and may be involved in the differentiation of epithelial cells into mesenchymal cells. Increased expression of GAPR-1 in kidney may contribute to the development of fibrosis.
抗原
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