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GCOM1 抗体 (AA 51-150) (Cy3)

This anti-GCOM1 antibody (ABIN1416749) is a Rabbit Polyclonal antibody detecting GCOM1 in WB, IF (cc), IF (p). Suitable for Mouse.
产品编号 ABIN1416749
发货至: 中国

Quick Overview for GCOM1 抗体 (AA 51-150) (Cy3) (ABIN1416749)

抗原

See all GCOM1 抗体
GCOM1 (GRINL1A Complex Locus (GCOM1))

适用

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小鼠

宿主

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克隆类型

  • 21
多克隆

标记

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This GCOM1 antibody is conjugated to Cy3

应用范围

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Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

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    AA 51-150

    交叉反应

    小鼠

    预测反应

    Human,Rat,Cow,Sheep,Horse,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human GCOM1

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    GCOM1 (GRINL1A Complex Locus (GCOM1))

    别名

    GCOM1

    背景

    Synonyms: Gcom2, Glutamate receptor ionotropic N methyl D aspartate like 1A combined, GRINL1A, GRINL1A combined protein, GRINL1A combined protein Gcom12, GRINL1A upstream protein, Gup1, Gup2, NMDAR1 subunit interacting protein.

    Background: Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Synaptic and extrasynaptic NMDA receptors have been shown to have opposite effects on neuronal survival, CREB function and gene regulation. Gcom1 (GRINL1A complex locus protein 1), also known as GUP (GRINL1A upstream protein) and Gcom (GRINL1A combined protein), is a 466 amino acid protein that is a component of the GRINL1A complex transcription unit, which is thought to be involved in the modulation of glutamatergic neurotransmission through interaction with the NR1 subunit of the NMDA receptor. Gcom1 is expressed in small intestine, lung, liver, heart, skeletal muscle, testis and prostate and also colocalizes with NR1 in cortical and hippocampal neurons. There are eleven isoforms of Gcom1 that are produced as a result of alternative splicing events.

    基因ID

    145781
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