UBE2O 抗体 (AA 1201-1292) (HRP)
Quick Overview for UBE2O 抗体 (AA 1201-1292) (HRP) (ABIN1416622)
抗原
See all UBE2O 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1201-1292
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预测反应
- Mouse,Rat,Pig,Horse,Chicken
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human UBE2O/E2 230K
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亚型
- IgG
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anti-Ubiquitin-Conjugating Enzyme E2O (UBE2O) (AA 1073-1292) antibody
UBE2O 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2O (UBE2O) (AA 361-470) antibodyUBE2O 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2C10 unconjugated
anti-Ubiquitin-Conjugating Enzyme E2O (UBE2O) (AA 10-277) antibodyUBE2O 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2O (UBE2O) (AA 1-741) antibodyUBE2O 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2O (UBE2O) (AA 1079-1128) antibodyUBE2O 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 猴, Pig, Bat, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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IHC-P 1:200-400
IHC-F 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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注意事项
- Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- UBE2O (Ubiquitin-Conjugating Enzyme E2O (UBE2O))
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别名
- UBE2O
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背景
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Synonyms: E2 230K, ubiquitin-conjugating enzyme E2O, EC=6.3.2.19, FLJ12878, KIAA1734, Likely Ortholog of Mouse Ubiquitin Conjugating Enzyme, RP23 193A16.5, UBE2O, UBE2O_HUMAN, Ubiquitin carrier protein O, Ubiquitin conjugating enzyme E2 O, ubiquitin conjugating enzyme E2O.
Background: UBE20, also known as E2-230K, is a 1,292 amino acid member of the uniquitin-conjugating enzyme family that is involved in protein modification. Expressed predominately in heart and skeletal muscle, UBE2O functions to catalyze the ATP-dependent covalent attachment of ubiquitin to select proteins, thereby targeting the ubiquitinated proteins for proteasomal degradation. The gene encoding UBE2O maps to human chromosome 17, which comprises over 2.5 % of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.
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基因ID
- 63893
抗原
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