TMPRSS6 抗体 (AA 711-811) (HRP)
Our Local Distributor
北京 101111
Quick Overview for TMPRSS6 抗体 (AA 711-811) (HRP) (ABIN1416142)
抗原
See all TMPRSS6 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 711-811
-
预测反应
- Human,Mouse,Rat,Dog,Cow,Chicken
-
纯化方法
- Purified by Protein A.
-
免疫原
- KLH conjugated synthetic peptide derived from human Matriptase 2
-
亚型
- IgG
-
-
anti-Transmembrane Protease, serine 6 (TMPRSS6) (AA 98-301) antibody
TMPRSS6 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Transmembrane Protease, serine 6 (TMPRSS6) (AA 85-114), (N-Term) antibodyTMPRSS6 适用: 人 WB 宿主: 兔 Polyclonal RB39227 unconjugated
anti-Transmembrane Protease, serine 6 (TMPRSS6) (AA 71-120) antibodyTMPRSS6 适用: 人, 小鼠, 大鼠, 豚鼠, 马, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Transmembrane Protease, serine 6 (TMPRSS6) (AA 711-811) antibodyTMPRSS6 适用: 人 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Transmembrane Protease, serine 6 (TMPRSS6) (AA 1-461) antibodyTMPRSS6 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
-
-
应用备注
-
WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
注意事项
- Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
-
有效期
- 12 months
-
-
- TMPRSS6 (Transmembrane Protease, serine 6 (TMPRSS6))
-
别名
- Matriptase 2
-
背景
-
Synonyms: Matriptase-2, Matriptase2, Membrane type serine proteinase 2, MTSP 2, MTSP2, PVAE354, TMPRSS 6, TMPRSS6, TMPS6_HUMAN, TMSP 6, TMSP6, Transmembrane protease serine 6, Type II Membrane Serine Proteinase 6.
Background: Serine protease which hydrolyzes a range of proteins including type I collagen, fibronectin and fibrinogen. Can also activate urokinase-type plasminogen activator with low efficiency. May play a specialized role in matrix remodeling processes in liver. Required to sense iron deficiency. Overexpression suppresses activation of the HAMP promoter.Involvement in disease:Defects in TMPRSS6 are the cause of iron-refractory iron deficiency anemia (IRIDA), also known as hypochromic microcytic anemia with defect in iron metabolism or hereditary iron-handling disorder or pseudo-iron-deficiency anemia. Key features include congenital hypochromic microcytic anemia, very low mean corpuscular erythrocyte volume, low transferrin saturation, abnormal iron absorption characterized by no hematologic improvement following treatment with oral iron, and abnormal iron utilization characterized by a sluggish, incomplete response to parenteral iron.
-
基因ID
- 164656
-
途径
- Transition Metal Ion Homeostasis
抗原
-
